Molecular Driving Forces, Second Edition is an introductory statistical thermodynamics text that describes the principles and forces that drive chemical and biological processes. It demonstrates how the complex behaviors of molecules can result from a few simple physical processes, and how simple models provide surprisingly accurate insights into the workings of the molecular world.
Widely adopted in its First Edition, Molecular Driving Forces is regarded by teachers and students as an accessible textbook that illuminates underlying principles and concepts. The Second Edition includes two brand new chapters: (1) "Microscopic Dynamics" introduces single molecule experiments; and (2) "Molecular Machines" considers how nanoscale machines and engines work. "The Logic of Thermodynamics" has been expanded to its own chapter and now covers heat, work, processes, pathways, and cycles. New practical applications, examples, and end-of-chapter questions are integrated throughout the revised and updated text, exploring topics in biology, environmental and energy science, and nanotechnology. Written in a clear and reader-friendly style, the book provides an excellent introduction to the subject for novices while remaining a valuable resource for experts.
Table of Contents
1: Principles of Probability
2: Extremum Principles Predict Equilibria
3: Heat, Work & Energy
4: Math Tools: Multivariate Calculus
5: Entropy & the Boltzmann Law
6: Thermodynamic Driving Forces
7: The Logic of Thermodynamics
8: Laboratory Conditions & Free Energies
9: Maxwell's Relations & Mixtures
10: The Boltzman Distribution Law
11: The Statistical Mechanics of Simple Gases & Solids
12: What Is Temperature? What Is Heat Capacity?
13: Chemical Equilibria
14: Equilibria Between Liquids, Solids, & Gases
15: Solutions & Mixtures
16: The Solvation & Transfer of Molecules Between Phases
17: Physical Kinetics: Diffusion, Permeation & Flow
18: Microscopic Dynamics
19: Chemical Kinetics & Transition States
20: Coulomb's Law of Electrostatic Forces
21: The Electrostatic Potential
22: Electrochemical Equilibria
23: Salt Ions Shield Charged Objects in Solution
24: Intermolecular Interactions
25: Phase Transitions
26: Cooperativity: The Hexlix-Coil, Isling & Landau Models
27: Adsorption, Binding & Catalysis
28: Multi-site & Cooperative Ligand Binding
29: Bio & Nano Machines
31: Water as a Solvent
32: Polymer Solutions
33: Polymer Elasticity & Collapse
34: Polymers Resist Confinement & Deformation
Ken A. Dill
Ken A. Dillis Professor of Pharmaceutical Chemistry and Biophysics at the University of California, San Francisco. He received his undergraduate training at MIT, his PhD from the University of California, San Diego, and did postdoctoral work at Stanford. A leading researcher in biopolymer statistical mechanics and protein folding, he has been the President of the Biophysical Society and received the Hans Neurath Award from the Protein Society in 1998.
Sarina Brombergreceived her BFA at the Cooper Union for the Advancement of Science and Art, her PhD in molecular biophysics from Wesleyan University, and her postdoctoral training at the University of California, San Francisco. She writes, edits and illustrates scientific textbooks.