1st Edition
Nanomaterials in Healthcare
This cutting-edge reference book discusses the biomedical applications of nanomaterials. It covers different types of nanoparticles, such as polymeric nanoparticles, lipoidal nanoparticles, and metallic nanoparticles. It discusses the current trends and challenges in the development of safe biomedicines. The book reviews FDA-approved medicines, nanohybrid systems for early-stage diagnosis and treatment of diseases, advanced approaches of cost-effective bio-imaging, and theragnostics. It also covers the basic design and fundamental understanding of surface-engineered biomedicine. The book is meant for experts in the healthcare industry as well as post-graduates in biomedical engineering and nanotechnology.
Preface
Acknowledgments
List of Reviewers
Editors
List of Contributors
1 Introduction to Nanomaterials and Their Scope in Drug Delivery
Pankaj Kumar, Uzma Afreen, and Sujit Kumar Debnath
2 Application of Nanomaterials in Medicine: A Clinical Perspective
Arnab Ghosh and Alyssa Gomes
3 Advancement of Polymer-Based Nanocarrier System in Drug Delivery
Pallavi Kiran, Abhinanda Kar, Arpita Banerjee, and Arzoo Puri
4 Liposomes and Lipid Structures: Classification, Characterization, and Nanotechnology-Based Clinical Applications
Suditi Neekhra, Priyanka Maske, and Roshan Keshari
5 Functionalized Carbon-Based Nanoparticles for Biomedical Application
Monalisha Debnath, Swati Patil, and Sujit Kumar Debnath
6 Engineered Magnetic Nanoparticles: Challenges and Prospects
Roshan Keshari and Bhingaradiya Nutan
7 Nano Metal-Organic Frameworks as a Promising Candidate for Biomedical Applications
Dhruv Menon, Swaroop Chakraborty, Prateek Goyal, Eugenia Valsami-Jones, and Superb K. Misra
8 Porous Silica Nanoparticles for Targeted Bio-Imaging and Drug Delivery Applications
Dhwani Rana, Raghav Gupta, Bharathi K., Rupali Pardhe, Nishant Kumar Jain, Sagar Salave, Rajendra Prasad, Derajram Benival, and Nagavendra Kommineni
9 Recent Advancement of Multifunctional ZnO Quantum Dots in the Biomedicine Field
Sayoni Sarkar, Jaisen Lokhande, and Sujit Kumar Debnath
10 Relevant Properties of Metallic and Non-Metallic Nanomaterials in Biomedical Applications
Parisa Fatehbasharzad, Pavlo Ivanchenko, Ola El Samrout, and Jaime Gómez Morales
11 Exosomes and Their Theragnostic Applications in Healthcare
Abhishekh Tiwari, Zainab Godhrawala, and Atul Chaskar
12 Nanogels for Theranostic Applications in Healthcare
Vaishali Pawar, Amreen Khan, Shruti Pendse, Rupali Bagale, Akshara Adapa, and Padmini Chandra
13 Theranostic Application of Nanofibers in Tissue Engineering
Atul Chaskar, Namrah Azmi, and Dhriti Shenoy
14 Role of Nanomaterials in Biosensing Applications
Jasmeen Kaur and Menam Pokhrel
15 Application of Two-Dimensional Materials for Cancer Theranostic
Barkha Singh and Ritika Uday Gaitonde
16 Solid Lipid Nanoparticles: Towards Emerging Cancer Nanomedicine
Amreen Khan, Vaishali Pawar, Rupali Bagale, Shruti Pendse, and Akshara Adapa
17 Gold Nanoparticles for Cancer Therapy and Diagnosis
Janhavi Devrukhkar and Jasmeen Kaur
18 Peptide-Based Nanoparticles for Theragnostic Application in Cancer Treatment
Pallavi Kiran, Vibha Kumari, Baishali A. Jana, and Prachi Kulkarni
19 Biomimetic Nanovesicles for Targeted Imaging and Therapeutic of Solid Tumor: Safe Nanomedicines
Fatemeh Salemizadehparizi, Rajendra Prasad, and Berivan Cecen
Index
Biography
Dr Rohit Srivastava is Dr Shanti Swarup Bhatnagar awardee, currently working as a Professor and Head at the Indian Institute of Technology Bombay. He completed his Master of Science and PhD degree in Biomedical Engineering from Louisiana Tech University, Ruston, LA, USA, for which he received the best student of the year award in 2005. Dr Srivastava holds various awards such as Healthcare Innovation Worldcup Award 2013, DBT IYBA Award 2013, DBT Tata Innovation Fellowship, Stanford MedTech Award 2016, DBT National Bioscience Award 2016, Shri Om Prakash Bhasin Award 2018, Abdul Kalam Technology Innovation National Fellowship, etc. Additionally, Dr Rohit Srivastava is an elected Fellow of the Royal Society of Chemistry (FRSC), Fellow of the Royal Society of Biology (FRSB), Fellow of NASI, and Fellow of INAE, etc. Dr Srivastava has published more than 200+ articles in international journals and conference proceedings with an h-index of 37. Further, he has participated in several book chapters and books. Nationally and internationally, His lab receives grants for most of all advanced science and technology domains. More than 130+ of his current ideas have been submitted as patents, and design applications to the US and Indian Patent Office, with several of them, have been approved.
Dr Sujit Kumar Debnath is working as an Industrial Post-Doctoral Fellow at Applied Materials India Pvt Ltd. He has completed his PhD in Pharmacy from Gujarat Technological University, Ahmedabad, in 2018. Afterward, he joined as Institute Post-Doctoral Fellow at the Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, India. He has more than 14 years of teaching and research experience. Dr Sujit works on smart and novel drug delivery systems using nanoparticulate approaches. He is well-versed in drug delivery, pre-clinical studies, toxicity, chromatographic estimation, and many more. He holds the GUJOST award from Gujarat Council on Science and Technology, Govt. of Gujarat under the Department of Science and Technology (DST). Nationally and internationally, Dr Sujit has been actively engaged in different collaborative projects. His contribution to science has gotten a brilliant reception from the worldwide scientific community. He has published 24 articles in various high-impact renowned journals and 3 book chapters in reputed publishers. He is frequently appointed as a guest lecturer. He also serves as an active reviewer in many reputable journals.
Dr Rajendra Prasad is currently working as an Assistant Professor at the Indian Institute of Technology-BHU, Varanasi, India. Before this position, he had postdoctoral experience from (i) Tufts University, Medford, MA, USA, (ii) Technion-Israel Institute of Technology, Haifa & NOVA Medical School, Faculdade de Ciências Médicas Campo Mártires da Pátria, Lisboa, Portugal and (iii) Indian Institute of Technology, Bombay, Powai, India. He works in cancer theranostics for solid tumor imaging and ablation. In 2017, Dr. Prasad earned his PhD degree from CSIR-National Chemical Laboratory, Pune, India, on multifunctional hybrid nanomaterials design for cancer theranostics. Dr Prasad mainly focuses on clinically relevant nanomedicines for cancer diagnosis and therapeutics. He has designed chemically conjugated multimode contrast and therapeutic agents such as liposomes, NanoBiosomes, Gold Nanorods, porous silica, drug-conjug ated hybrids, etc., and has investigated them in pre-clinical models. He is well-versed in pre-clinical trials and light-mediated combination cancer therapeutics. To date, he has published about 23 research articles in top-tier journals, about 11 patents, 7 trademarks, 5 journal cover arts, and 2 book chapters with an h-index of 13. Dr Prasad holds awards like the best paper award, PBC Fellow, SAS Fellow, etc.
