Nanotechnology in Biology and Medicine : Research Advancements & Future Perspectives book cover
1st Edition

Nanotechnology in Biology and Medicine
Research Advancements & Future Perspectives

ISBN 9780367200503
Published October 25, 2019 by CRC Press
291 Pages 97 B/W Illustrations

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Book Description

Nanotechnology in biology and medicine: Research advancements & future perspectives is focused to provide an interdisciplinary, integrative overview on the developments made in nanotechnology till date along with the ongoing trends and the future prospects. It presents the basics, fundamental results/current applications and latest achievements on nanobiotechnological researches worldwide scientific era. One of the major goals of this book is to highlight the multifaceted issues on or surrounding of nanotechnology on the basis of case studies, academic and theoretical articles, technology transfer (patents and copyrights), innovation, economics and policy management.

Moreover, a large variety of nanobio-analytical methods are presented as a core asset to the early career researchers. This book has been designed for scientists, academician, students and entrepreneurs engaged in nanotechnology research and development. Nonetheless, it should be of interest to a variety of scientific disciplines including agriculture, medicine, drug and food material sciences and consumer products.


  • It provides a thoroughly comprehensive overview of all major aspects of nanobiotechnology, considering the technology, applications, and socio-economic context
  • It integrates physics, biology, and chemistry of nanosystems
  • It reflects the state-of-the-art in nanotechnological research (biomedical, food, agriculture)
  • It presents the application of nanotechnology in biomedical field including diagnostics and therapeutics (drug discovery, screening and delivery)
  • It also discusses research involving gene therapy, cancer nanotheranostics, nano sensors, lab-on-a-chip techniques, etc.
  • It provides the information about health risks of nanotechnology and potential remedies.
  • It offers a timely forum for peer-reviewed research with extensive references within each chapter

Table of Contents

Section 1: Nanoscale Materials: Design, Manufacture, and Physicochemical Properties

1. Polymeric Nanostructures: Their Synthesis Approaches and Morphological and Physicochemical Characterizations

[Debasis Nayak and Pradipta Ranjan Rauta]

2. Synthesis, Characterization, and Applications of Silica Nanomaterials from a Nanobiotechnological Perspective

[Chityal Ganesh Kumar, Kanugala Sirisha, and Puvvada Naga Prasad]

3. Assessing Interactions of Microalgae in Synthesizing Nanoparticles

[Manoj Kumar Enamala, Azzuliani Binti Supangat, Chandrasekhar Kuppam, Sudhakar Reddy Pamanji, Murthy Chavali, and Maria P. Nikolova]

4. Liposome Nanocarrier: Synthesis, Characterization, and Applications

[Prabhu Sukumaran and V. Sandhya]

Section 2: Nano Biotechnology Applications on Food and Agriculture

5. New Insights into the Pharmaceutical and Food-Based Applications of Starch Nanocrystals

[Neethu Hari, Supriya Radhakrishnan, Athira S. Dev, and Ananthakrishnan Jayakumaran Nair]

6. Recent Developments on Nanotechnology in Agriculture: Challenges and Prospects

[Yugal Kishore Mohanta, Tapan Kumar Mohanta, and Debasis Nayak]

7. An Overview of Mycogenic Nanoparticles: Synthesis and Their Bio-Prospective Applications

[Sagarika Mohanta, Sameer Kumar Singdevsachan, Yugal Kishore Mohanta, Sujogya Kumar Panda, and Tapan Kumar Mohanta]

8. Nanonutraceutical Delivery Systems: Application in Food and Feed Industry

[Visha Pasuvalingam]

Section 3: Nano Biotechnology in Health Care/Therapeutic Applications

9. Nanomedicine for Wound Healing: Challenges and Future Perspectives

[Sourav Das, Papia Basu Thakur, Aparna Harri, Manali Bagade, and Chitta Ranjan Patra]

10. Recent Advancements on Nano-Based Drug Delivery System for Targeted Cancer Therapy

[Arindam Pramanik]

11. Recent Nanotechnological Advancements in Delivery of Peptide and Protein Macromolecules

[Sunita Dahiya and Rajiv Dahiya]

12. Nanotechnology: The Hope for New Generation and Its Therapeutic Applications

[Dnyaneshwar Rathod, Avinash Kharat, Varsha Wankhade, and Mahendra Rai]

13. Origami-Engineered Structures and Their Biomedical Applications

[Dipti Mohanta, Snehaprava Mohapatra, Sonali Khuntia, Suchilagna Sahoo, and Pradipta Ranjan Rauta]

Section 4: Biosensors/Nanochip/Nanodevice/Nanocomputing

14. Nanobiosensors and Their Biomedical Applications

[Pradipta Ranjan Rauta, Debasis Nayak, and Pankaj Kumar Singh]

15. Theranostic Advances of Graphene-Based Nanomaterial in Diabetes

[Kunal Biswas, Siddharth Shaw, Sudhanshu Mishra, Debashis De, and Jaya Bandyopadhyay]

16. Role of Gold Nanoparticles (GNPs) in Cancer Diagnosis and Treatment

[Kalpana Panati, Parasuraman Aiya Subramani, Dharaneeswara Reddy Devireddy, and Venkata Ramireddy Narala]

17. Graphene: A Revolutionary 2D Nanomaterial Heralding a New Horizon for Diagnostics and Therapeutic Applications

[Kunal Biswas, Debashis De, and Jaya Bandyopadhyay]

18. Applications of Nanosensor System in the Detection of Heavy Metals

[Arun Kumar Pradhan and Soudamini Acharya]

Section 5: Nanobiotecnology: Health Safety Toxicity and Environmental Impact

19. Epigenetic Landscape–Modifying Nanoparticles

[Dipta Sengupta and Debasis Nayak]

20. Nanotoxicology: Evaluating Toxic Potential of Drug Nanoparticles

[Pavani Gonnabathula, Nageswararao Mekala, and Praveen Kumar Relangi]

21. Nanobioremediation: A Novel and Sustainable Biological Advancement for Ecological Cleanup

[Manoj Kumar Enamala, P. Divya Sruthi, Silpi Sarkar, Murthy Chavali, Induri Vasavi, and Chandrashekar Kuppam]

22. Nanotoxicity: Physicochemical and Biological (PK-PD) Perspectives

[Mithun Rudrapal, Dipak Chetia, Khomendra Kumar Sarwa, and Soumya Bhattacharya]

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Pradipta Ranjan Rauta is a Postdoctoral Research Fellow at the Center for Radiation Oncology Research, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. He earned his PhD in Life Science from National Institute of Technology, Rourkela, Odisha, India; MSc. in Microbiology from Orissa University of Agriculture and Technology, Bhubaneswar, Odisha, India; BSc in Zoology from Utkal University, Bhubaneswar, Orissa, India. He had also worked as PhD mobility fellow at Instituto Superior Técnico, Lisboa, Portugal during his PhD through Erasmus Mundus fellowship program. Dr. Rauta has more than 10 year research experience in various fields i.e. microbiology, immunology, molecular biology, nanotechnology and cell biology. He has published 23 peer-reviewed journal articles, 2 popular articles, and has presented at many international conferences. He has expertise on nano biomedical research in the following areas: nanotechnology, cell biology, proteomics, molecular biology, immunology, in vivo study and bio techniques (instrumentation) etc. His research areas are mainly involved in developing smart delivery systems for anticancer drugs targeting cancer. Specifically, he has developed multifunctional nanoplatforms comprising a biocompatible polymer, an anticancer drug and cancer-specific ligands that specifically and efficiently target only cancer cells, thereby significantly reducing systemic toxicity in response to chemotherapy. This involves, but is not limited to, fabrication of polymeric nanoparticles, effective drug encapsulation, controlled drug release, functionalization with cancer cell specific ligands for specific targeting and to achieve enhanced therapeutic efficacy of drugs without systemic toxicity. His current research is focused on designing novel multifunctional gold-based nanotheranostics for advanced cancer. Dr. Rauta has actively contributed to all phases of the research project like concept development and design, wet-lab experiments, data analysis and manuscript (and, grant) preparation. He is associated with many scientific societies as a fellow member such as Indian Science Congress Association, American Society for Microbiology etc. He has reviewed many research articles for international journals from Elsevier, Springer etc. He is also serving as review editor for international journals such as frontiers in Bioengineering & Biotechnology and frontiers in Molecular Biosciences.

Yugal Kishore Mohanta is working as Research Scientist at Biochemistry Laboratory, Department of Botany, North Orissa University, Baripada, India. He has received his PhD in Life Sciences from North Orissa University, Baripada, India. He has also successfully completed the BCIL industrial training programme on Plant Tissue Culture sponsored by Department of Biotechnology, Govt. of India, New Delhi. Among other academic/research achievements, he was awarded as visiting research scholar at Department of Biology, KU Leuven, Belgium sponsored by KU Leuven. Dr. Mohanta has more than 9 years of post-M.Sc. research experience on natural products chemistry, nanotechnology, microbiology and plant biotechnology. He has published 21 research articles, 8 book chapters, 5 popular science articles, and has presented in many national and international conferences. He is currently working on the application of nanotechnology on different aspects such as food safety, biomedical and conservation of natural resources. Besides such scientific activities, Dr. Mohanta is passionately involved in Wildlife Photography and Nature Conservation. Currently he is working as volunteer in the moments like “WeR4River” and “Youth4River” for conservation of Rivers and Water Resources. He is also serving as reviewer in many international journals from Elsevier, Springer etc. 
Debasis Nayak is an Assistant Professor and Head in the Department of Zoology, Seemanta Mahavidyalaya, Jharpokharia, Mayurbhanj, Odisha, India. Dr. Nayak has earned his PhD in Life Science, National Institute of Technology Rourkela, Odisha, India. M.Sc. in Life Science from Nation Institute of Technology Rourkela, Odisha, India and B.Sc. with Zoology (Honors) from Govt. (Autonomous) College, Rourkela, Odisha, India. Dr. Nayak has research experience of 7 years in nanotechnology, microbiology, immunology and molecular biology. He has published 15 research articles in peer reviewed international journals and has attended and presented in many international conferences. Dr. Nayak has expertise in synthesis of metallic nanoparticles through green synthesis route, preparation of novel drug delivery carriers using gelatin, carrageenan, chitosan and various natural and synthetic polymers for oral, transdermal and parenteral drug delivery. He has wide expertise on handling high end instruments such as scanning electron microscope, Atomic force microscope, XRD, FTIR, flow cytometer and fluorescence microscope. His research is mainly focused on development of cost effective and novel therapeutics using indigenous materials as anticancer agents by inducing oxidative stress and mitochondrial damage inside the specific cancer cell without affecting the neighboring normal cells devoid of any additional side effects. Dr. Nayak has reviewed many research articles for international journals and his current research interest are on developing topical gels and ointments containing novel indigenous phytochemicals and organic and inorganic nanoparticles against various forms of cutaneous and malignant skin carcinomas.