Nanotechnology in Biology and Medicine: Research Advancements & Future Perspectives, 1st Edition (Hardback) book cover

Nanotechnology in Biology and Medicine

Research Advancements & Future Perspectives, 1st Edition

Edited by Pradipta Ranjan Rauta, Yugal Kishore Mohanta, Debasis Nayak

CRC Press

328 pages | 97 B/W Illus.

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Hardback: 9780367200503
pub: 2019-11-04
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Nanotechnology in biology and medicine: Research advancements & future perspectives is focused to provide an interdisciplinary, integrative overview on the developments made in nanotechnology till date along with the ongoing trends and the future prospects. It presents the basics, fundamental results/current applications and latest achievements on nanobiotechnological researches worldwide scientific era. One of the major goals of this book is to highlight the multifaceted issues on or surrounding of nanotechnology on the basis of case studies, academic and theoretical articles, technology transfer (patents and copyrights), innovation, economics and policy management.

Moreover, a large variety of nanobio-analytical methods are presented as a core asset to the early career researchers. This book has been designed for scientists, academician, students and entrepreneurs engaged in nanotechnology research and development. Nonetheless, it should be of interest to a variety of scientific disciplines including agriculture, medicine, drug and food material sciences and consumer products.


  • It provides a thoroughly comprehensive overview of all major aspects of nanobiotechnology, considering the technology, applications, and socio-economic context
  • It integrates physics, biology, and chemistry of nanosystems
  • It reflects the state-of-the-art in nanotechnological research (biomedical, food, agriculture)
  • It presents the application of nanotechnology in biomedical field including diagnostics and therapeutics (drug discovery, screening and delivery)
  • It also discusses research involving gene therapy, cancer nanotheranostics, nano sensors, lab-on-a-chip techniques, etc.
  • It provides the information about health risks of nanotechnology and potential remedies.
  • It offers a timely forum for peer-reviewed research with extensive references within each chapter

Table of Contents

Section 1: Nanoscale materials: Design, manufacture, and physicochemical properties

Chapter 1: Polymeric nanostructures: their synthesis approaches, morphological and physicochemical characterizations;

Debasis Nayak, Pradipta Ranjan Rauta

Chapter 2: Synthesis, Characterization and Applications of Silica Nanomaterials from a Nanobiotechnological Perspective

Chityal Ganesh Kumar, Kanugala Sirisha and Puvvada Naga Prasad

Chapter 3: Assessing interactions of microalgae in synthesizing nanoparticles

Manoj Kumar Enamala, Azzuliani Binti Supangat, Kuppam Chandrashekar, Sudhakar Reddy Pamanji, Murthy Chavali and Maria P. Nikolova

Chapter 4: Liposome nanocarrier- synthesis, characterization and applications

S. Prabhu and V. Sandhya

Section 2: Nano biotechnology applications on Food and Agriculture

Chapter 5: New Insights into the Pharmaceutical and Food Based Applications of Starch Nanocrystals

Neethu H., Supriya R., Athira S. D., Ananthakrishnan. J. N.

Chapter 6: Recent Developments on Nanotechnology in Agriculture: Challenges and Prospects

Yugal Kishore Mohanta, Tapan Kumar Mohanta and Debasis Nayak

Chapter 7: An overview of mycogenic nanoparticles: Synthesis and their bio-prospective applications

Sagarika Mohanta, Sameer Kumar Singdevsachan, Yugal Kishore Mohanta, Sujogya Kumar Panda and Tapan Kumar Mohanta


Chapter 8: Nanonutraceutical Delivery Systems: Application in Food and Feed industry

Visha Pasuvalingam


Section 3: Nano biotechnology in health care/therapeutic applications

Chapter 9: Nanomedicine for wound healing: Challenges and Future Perspectives

Sourav Das, Papia Basu Thakur, Aparna Harri, Manali Bagade, Chitta Ranjan Patra

Chapter 10: Cancer therapy by targeted drug delivery of novel metal and organo-metallic nano complexes

Arindam Pramanik


Chapter 11: Recent Nanotechnological Advancements in Delivery of Peptide and Protein Macromolecules

Sunita Dahiya1, Rajiv Dahiya2.

Chapter 12: Nanotechnology the hope for new generation and its therapeutic applications Dnyaneshwar Rathod, Avinash Kharat, Varsha Wankhade, Mahendra Rai

Chapter 13: Origami-engineered structures and their biomedical applications

Dipti Mohanta, Snehaprava Mohapatra, Sonali Khuntia, Suchilagna Sahoo and Pradipta Ranjan Rauta

Section 4: Biosensors/nanochip/nanodevice/nanocomputing

Chapter 14: Nanobiosensors and their biomedical applications

Pradipta Ranjan Rauta, Debasis Nayak, Pankaj Kumar Singh

Chapter 15: Theranostic advances of graphene based nanomaterial in diabetes

Kunal Biswas, Siddharth Shaw, Shudhanshu Mishra, Debashis De and Jaya Bandyopadhyay

Chapter 16: Role of gold nanoparticles (GNPs) in cancer diagnosis and treatment

Kalpana Panati, Parasuraman Aiya Subramani, Dharaneeswara Reddy Devireddy, Venkata Ramireddy Narala

Chapter 17: Graphene: A revolutionary 2D nanomaterial heralding a new horizon for diagnostics and therapeutic applications

Kunal Biswas, Debashis De and Jaya Bandyopadhyay

Chapter 18: Applications of Nanosensor System in the Detection of Heavy Metals

Arun Kumar Pradhan and Soudamini Acharya

Section 5: Nanobiotecnology: health safety toxicity and environmental impact

Chapter 19: Epigenetics landscape modifying nanoparticles

Dipta Sengupta and Debasis Nayak

Chapter 20: Nanotoxicology: Evaluating Toxic potential of drug- nanoparticles

Pavani Gonnabathula, Nageswararao Mekala, Praveen Kumar Relangi.

Chapter 21: Nanobioremediation: A novel and sustainable biological advancement for ecological clean-up

Manoj Kumar Enamala, P. Divya Sruthi, Silpi Sarkar, Murthy Chavali, Induri Vasavi, Chandrashekar Kuppam

Chapter 22: Nanotoxicity: Physicochemical and Biological (PK-PD) Perspectives

M. Rudrapal, D. Chetia, K. K. Sarwa and S. Bhattacharya



About the Editors

Pradipta Ranjan Rauta is a Postdoctoral Research Fellow at the Center for Radiation Oncology Research, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. He earned his PhD in Life Science from National Institute of Technology, Rourkela, Odisha, India; MSc. in Microbiology from Orissa University of Agriculture and Technology, Bhubaneswar, Odisha, India; BSc in Zoology from Utkal University, Bhubaneswar, Orissa, India. He had also worked as PhD mobility fellow at Instituto Superior Técnico, Lisboa, Portugal during his PhD through Erasmus Mundus fellowship program. Dr. Rauta has more than 10 year research experience in various fields i.e. microbiology, immunology, molecular biology, nanotechnology and cell biology. He has published 23 peer-reviewed journal articles, 2 popular articles, and has presented at many international conferences. He has expertise on nano biomedical research in the following areas: nanotechnology, cell biology, proteomics, molecular biology, immunology, in vivo study and bio techniques (instrumentation) etc. His research areas are mainly involved in developing smart delivery systems for anticancer drugs targeting cancer. Specifically, he has developed multifunctional nanoplatforms comprising a biocompatible polymer, an anticancer drug and cancer-specific ligands that specifically and efficiently target only cancer cells, thereby significantly reducing systemic toxicity in response to chemotherapy. This involves, but is not limited to, fabrication of polymeric nanoparticles, effective drug encapsulation, controlled drug release, functionalization with cancer cell specific ligands for specific targeting and to achieve enhanced therapeutic efficacy of drugs without systemic toxicity. His current research is focused on designing novel multifunctional gold-based nanotheranostics for advanced cancer. Dr. Rauta has actively contributed to all phases of the research project like concept development and design, wet-lab experiments, data analysis and manuscript (and, grant) preparation. He is associated with many scientific societies as a fellow member such as Indian Science Congress Association, American Society for Microbiology etc. He has reviewed many research articles for international journals from Elsevier, Springer etc. He is also serving as review editor for international journals such as frontiers in Bioengineering & Biotechnology and frontiers in Molecular Biosciences.

Yugal Kishore Mohanta is working as Research Scientist at Biochemistry Laboratory, Department of Botany, North Orissa University, Baripada, India. He has received his PhD in Life Sciences from North Orissa University, Baripada, India. He has also successfully completed the BCIL industrial training programme on Plant Tissue Culture sponsored by Department of Biotechnology, Govt. of India, New Delhi. Among other academic/research achievements, he was awarded as visiting research scholar at Department of Biology, KU Leuven, Belgium sponsored by KU Leuven. Dr. Mohanta has more than 9 years of post-M.Sc. research experience on natural products chemistry, nanotechnology, microbiology and plant biotechnology. He has published 21 research articles, 8 book chapters, 5 popular science articles, and has presented in many national and international conferences. He is currently working on the application of nanotechnology on different aspects such as food safety, biomedical and conservation of natural resources. Besides such scientific activities, Dr. Mohanta is passionately involved in Wildlife Photography and Nature Conservation. Currently he is working as volunteer in the moments like “WeR4River” and “Youth4River” for conservation of Rivers and Water Resources. He is also serving as reviewer in many international journals from Elsevier, Springer etc.

Debasis Nayak is an Assistant Professor and Head in the Department of Zoology, Seemanta Mahavidyalaya, Jharpokharia, Mayurbhanj, Odisha, India. Dr. Nayak has earned his PhD in Life Science, National Institute of Technology Rourkela, Odisha, India. M.Sc. in Life Science from Nation Institute of Technology Rourkela, Odisha, India and B.Sc. with Zoology (Honors) from Govt. (Autonomous) College, Rourkela, Odisha, India. Dr. Nayak has research experience of 7 years in nanotechnology, microbiology, immunology and molecular biology. He has published 15 research articles in peer reviewed international journals and has attended and presented in many international conferences. Dr. Nayak has expertise in synthesis of metallic nanoparticles through green synthesis route, preparation of novel drug delivery carriers using gelatin, carrageenan, chitosan and various natural and synthetic polymers for oral, transdermal and parenteral drug delivery. He has wide expertise on handling high end instruments such as scanning electron microscope, Atomic force microscope, XRD, FTIR, flow cytometer and fluorescence microscope. His research is mainly focused on development of cost effective and novel therapeutics using indigenous materials as anticancer agents by inducing oxidative stress and mitochondrial damage inside the specific cancer cell without affecting the neighboring normal cells devoid of any additional side effects. Dr. Nayak has reviewed many research articles for international journals and his current research interest are on developing topical gels and ointments containing novel indigenous phytochemicals and organic and inorganic nanoparticles against various forms of cutaneous and malignant skin carcinomas.

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Biochemistry
MEDICAL / Biotechnology
SCIENCE / Life Sciences / General