Globally, natural medicine has been considered as an important alternative to modern allopathic medicine. Although natural medicines are popular in society, only limited medicinal herbs have been scientifically evaluated for their potential in medical treatment. This book connects various aspects of the complex journey from traditional medicine to modern medicine. It provides information on topics including global regulations and regulatory hurdles, diverse nutritional challenges and potential health benefits, novel food innovations especially seed-to-clinic approaches, and future trends.
• Provides information on sustainable use of natural products in the development of new drugs and clinically validated herbal remedies
• Discusses issues on evaluation and clinical aspects of herbal medicine, promotion and development, safety evaluation, metabolite profiling, biomarker analysis, formulation, and stability testing
• Describes traditional uses of natural medicine through identification, isolation and structural characterization of their active components
• Elucidates mechanisms of biological action, adverse effects and identification of their molecular targets of natural medicine
• Multidisciplinary appeal including chemistry, pharmacology, pharmacognosy and cell and molecular biology, as well as integration with clinical medicine
This book serves as an essential guide for individuals researching natural medicines, and industry employees in areas including drug development, pharmacology, natural products chemistry, clinical efficacy, ethnopharmacology, pharmacognosy, phytotherapy, phyto-technology and herbal science.
Table of Contents
Section I: Quality and Chemistry. 1. Efficacy, Quality, Safety and Toxicity of Herbal Medicine: Safeguarding Public Health. 2. Standardisation and Quality Control of Herbal Medicines: From Raw Materials to Finished Products. 3. Structure-Function Elucidation of Flavonoids by Modern Technologies: Role in Management of Diabetes and Cancer. 4. Tanshinone Diterpenes: Chemistry and Multifunctional Biological Activities. 5. Bacognize: A Standardised Extract of Bacopa monnieri. 6. Role of Process Standardisation in Development of Natural Products. 7. Biomarkers for Quality Control of Chinese Tonifying Herbs and Herbal Health Products. 8. Nelumbo nucifera: Pharmacological Profile, Metabolite Profiling and Therapeutic Uses. Section II: Safety. 9. Safety and Toxicity of Medicinal Plants: Concerns and Overview. 10. Approaches to Safety Evaluation of Botanicals and Processed Botanicals Known in Traditional Knowledge. Section III: Regulation. 11. Korea’s Health Functional Food Classification. 12. Phytopharmaceuticals: Unique Regulatory Category with Immense Potential for Medical Unmet Needs. Section IV: Clinical Efficacy. 13. Cranberry Proanthocyanidins (PACs) in Bacterial Anti-Adhesion. 14. The Promise for Alzheimer’s Disease Treatment: Bioactive Compounds. 15. ENZOGENOL Pine Bark Extract: From an Ancient Remedy to a Natural Neurotherapeutic. 16. Current State of Clinical Translation of Natural Cardioprotective Agents. 17. Herbal Products in Antihypertensive Therapy: Potentialities and Challenges – A Brazilian Perspective. 18. Role of the Ayurvedic Medicinal Herb Bacopa monnieri in Child and Adolescent Populations. 19. Recent Insights on the Role of Natural Medicines in Immunostimulation. 20. Clinical Trial Protocol for Herbal Drugs: Perspectives of India. 21. Nanotechnology and Anti-Ageing Skin Care. Section V: Reviews. 22. Anredera cordifolia (Ten.) v. Steenis: A New Emerging Cure with Polypharmacological Effects. 23. Medicinal Properties of Ginger (Zingiber officinale Roscoe). 24. Single Herb to Single Phytochemical–Based Therapy for Diabetes Mellitus. 25. Phytochemical, Pharmacological and Therapeutic Profile of Bacopa monnieri: A Prospective Complementary Medicine. 26. Natural Medicines: Categories, Comebacks and Catalysts. 27. Management of Diabetes and Hyperlipidaemia by Natural Medicines. 28. Globalisation of Traditional Medicine under the Modern Medicine Portfolio. 29. Cannabis and Cannabinoids: A Journey from an Ancient Belief to the Fore. 30. Shifts in Global Healthcare. 31. Ayurveda: Evidence-Based Approach for Drug Development. 32. Natural Medicine: Potential in Public Healthcare and Research with Specific Focus on Ayurveda.
Dilip Ghosh, PhD, FACN is an international speaker, facilitator and author and professionally associated with SOHO-Flordis International (SFI), Australia; Honorary Ambassador, Global Harmonization Initiative (GHI), University of Western Sydney. With more than 20 years of experience in both pharmaceutical and food-nutrition industries, he is one of the pioneer researchers in the evaluation of the health claim opportunities of potential functional food ingredients and complementary medicines through an evaluation of the current scientific evidence base and related claims, and provides commentary on gaps in science including potential requirements for research such as human studies.
Pulok K. Mukherjee, PhD is the Director of the School of Natural Product Studies, Jadavpur University, Kolkata, India. His research/academic work highlights traditional medicine inspired by drug discovery from Indian medicinal plants to make them available from ‘Farm to Pharma’. His research includes validation of medicinal plants from India systems of medicine, their formulation and standardization, which are useful bio-prospecting tools for the traditional medicine based drug discovery programme.