1st Edition
Natural Products and Nano-Formulations in Cancer Chemoprevention
This book covers various aspects of cancer chemoprevention, including an overview of chemoprevention in the process of tumorigenesis; the roles of various phytochemicals, functional foods, and dietary interventions in disease prevention; and techniques such as cancer stem cell targeting, nano-formulations, and so forth.
The nutrigenomic and epigenetic effects of natural products at the molecular and genetic levels are also covered alongside their potential for additive and synergistic effect, as well as overcoming drug resistance. The key selling features of the book are as follows:
- Discusses holistic and comprehensive areas of chemoprevention
- Includes diverse techniques, such as cancer stem cell targeting, nano-formulations, and nanotechnology-based drug delivery systems
- Introduces various mechanisms involved in prevention of the diseases, including targeting cancer stem cells
- Reviews various aspects which can reduce the toxicity and cost of treatment of diseases by alternative medicine
- Explores various sources, mechanisms, and ways to develop cancer chemopreventive agents with minimal toxicity compared to traditional cancer therapy drugs
This book is focused on researchers and graduate students in drug delivery and formulation, nanobiotechnology, cancer chemoprevention, prevention, and therapeutics.
1 Overview of Natural Products and Nano-Formulations in Cancer Chemoprevention
Ananya Bahuguna, Shiv Kumar Dubey, Kanchan Gairola, and Rohit Pujari
2 Polyphenols in Cancer Chemoprevention
Pushpendra Koli, Dinesh K. Yadav, Mahesh K. Samota, and Sandeep Kumar
3 Fat-Soluble Vitamins in Cancer Chemoprevention
Neetika Naudiyal, Gaurav Singh Rana, Ankur Adhikari, and Shiv Kumar Dubey
4 Targeting Cancer Stem Cells by Natural Products for Chemoprevention
Kamana Singh, Prabha Arya, and Ram Sunil Kumar L.
5 Functional Foods in Cancer Chemoprevention and Therapeutics
Shreya Joshi, Pranshu Sharma, and Atul Kumar Joshi
6 Phytochemicals: Potential Source of Interventions in Cancer Prevention and Treatment
Sonu Kumar Mahawer, Himani, Sushila Arya, Tanuja Kabdal, Ravendra Kumar, and Om Prakash
7 Nano-Formulation-Based Approaches for Chemoprevention
Dipanjana Ghosh, Wean Sin Cheow, and Rohit Saluja
8 Potential of Natural-Product-Based Nano-Formulations as Chemopreventive Agents
Sneh Gautam, Pushpa Lohani, Shiv Dutt Purohit, Sonu Ambawani, and Pooam Maan
9 Nano-Formulations of Chemotherapeutic Drugs: Recent Outlook, Advances, and Challenges in Cancer Management
Deepa Bisht, Shilpa Maddheshiya, Seema Nara, and Manisha Sachan
10 Nutrigenomics in Cancer Chemoprevention
Kanchan Gairola, Shiv Kumar Dubey, Ananya Bahuguna, and Shruti
11 Synergistic Effects of Natural Products in Cancer Treatment
Ritu Saini, Chitra Gupta, Shalini Pundir, Meenakshi Bajpai, Akansha Agrwal, and Sharad Visht
12 Medicinal Chemistry, Pharmacodynamics, and Pharmacokinetics of Camptothecin and Its Derivatives in Clinical Chemotherapeutics
Thadiyan Parambil Ijinu, Parameswaran Sasikumar, Vandhanam Aparna, Sreejith Pongillyathundiyil Sasidharan, Vipin Mohan Dan, Farkhodjon Tukhtaev, Varughese George, and Palpu Pushpangadan
13 Brassica Phytochemicals: A Potential Source of Cancer Prevention and Treatment
Himanshu Punetha and Shivanshu Garg
14 Opportunities with Nano-Formulations in Cancer Chemoprevention
Akansha Agrwal and Sheetal Mittal
15 Obstacles in Utilizing Nanomedicine for Cancer Management
Kamana Singh, Vineeta Kashyap, and Addanki P Kumar
16 Mangroves as an Alternative Source of Anticancer Drug Leads: Current Evidence and Future Prospects
Vasantha Kavunkal Hridya, Kokkuvayil Vasu Radhakrishnan, Nainarpandiyan Chandrasekar, and Thadiyan Parambil Ijinu
Biography
Dr. Shiv Kumar Dubey is Assistant Professor in the Biochemistry Department at the College of Basic Sciences and Humanities, G. B. Pant University of Agriculture and Technology in Pantnagar, India, since 2015. He completed his master's and bachelor's degrees at the University of Allahabad in Uttar Pradesh, India, where he also accomplished his PhD degree. He pursued his postdoctoral research at the Institute of Pharmacology and Structural Biology, CNRS, Toulouse, France, and at the University of Michigan Cancer Comprehensive Center, Ann Arbor, Michigan, USA.
His numerous fellowships, including the NET-JRF (National Eligibility Test for Junior Research Fellowship), given by the UGC-CSIR in India, have been awarded to Dr. Shiv Kumar Dubey. More than 25 research papers, book chapters, and reviews by Dr. Dueby have been published in reputable national and international journals. The results of his research have also been presented in numerous national and international forums, including conferences, seminars, and symposiums. Dr. Dubey has created a number of e-content modules and organized webinars and e-training sessions for the benefit of students. To his credit, he has supervised many student theses, led patents, and developed many courses for undergraduate and postgraduate students. He is actively engaged in the areas of advanced biochemistry, chemoprevention, and natural product research. His work has considerably impacted the study of appropriately constructed curcumin bioconjugates, the validation of analytical methods, the effectiveness of nutraceuticals, and the development of their synthetic analogs for the treatment of cancer. His pursuit of bioprospecting of novel natural compounds for cancer chemoprevention is ongoing.
