1st Edition

Neuro-Nutraceuticals and Drug Discovery and Delivery in Alzheimer’s Disease Volume 2: Strategies to Unlock the Brain’s Fortress

Edited By Varinder Singh, Amit Kumar, Parul Sood Copyright 2025
322 Pages 33 B/W Illustrations
by Apple Academic Press

322 Pages 33 B/W Illustrations
by Apple Academic Press

The number of people living with dementia is expected to rise from 55 million in 2019 to 139 million in 2050, according to a report by WHO. Conventional drugs, while providing symptomatic relief, have often fallen short of halting the relentless progression of this neurodegenerative disorder. This new two-volume set represents a collective effort to delve into the potential of nature’s... Read more

PART I: NUTRACEUTICALS: HOLISTIC APPROACHES TO ALZHEIMER’S MANAGEMENT

1. Emergent Natural Antioxidant Therapeutics to Cope with Oxidative Stress in Alzheimer’s Disease

Anandita Gulati, Rajwinder Kaur, Damanpreet Kaur Lang, Nidhi Rani, and Balakumar Chandrasekaran

2. Exploring Beta Secretase Inhibitors as the Evergreen Drug Target for Alzheimer’s Disease: Calling Herbal Therapies to the Rescue

Shiveena Bhatia, Manjinder Singh, Amit Kumar, Varinder Singh, Kavita Munjal, Mohit Kumar, Tanveer Singh, and Hasandeep Singh

3. Role of Natural Steroidal Phytopharmaceuticals in the Management of Alzheimer’s Disease

Pallavi Bassi, Sushma Devi, Shivani Rana, Ankita Thakur, and Jangjeet Karan Singh

4. Potential Role of Terpenes in the Management of Alzheimer’s Disease

Diksha Sharma, Amit Kumar, Ayushi Negi, Manjinder Singh, Varinder Singh, and Mohit Kumar

5. Anti-Apoptotic Natural Products for the Management of Alzheimer’s Disease

Hasandeep Singh, Gurpreet Singh, Loveleen Kaur, Sarabjit Kaur, Gurkiran Kaur, Gurbaj Singh, Balbir Singh, and Varinder Singh

6. Potential Natural Polysaccharides for the Management of Alzheimer’s Disease

Sonia Dhiman, Devanshi Mehta, and Thakur Gurjeet Singh

7. Neuro-Protective Role of Vitamin D in Alzheimer’s Disease

Sarita Jangra, Bhupinder Bhyan, Preetpal Singh, Lakshita Taneja, Shweta Maan, Tanya Sood, Shaima Ka, Nishant Johri, and Ravinder Singh

8. Role of Non-Flavonoidal Agents in Alzheimer’s Disease

Shreya Sood, Neeraj Mittal, Gagandeep Kaur, Sima Singh, and Sushma Devi

PART II: RECENT DEVELOPMENTS AND ADVANCEMENTS IN THE DELIVERY OF NUTRACEUTICALS ACROSS BLOOD-BRAIN-BARRIER

9. Drug Delivery Strategies for Drug Targeting for Alzheimer’s Disease

Divyasree Kandipati, Jyoti Dange, Teenu Sharma, Manish Kumar Jeengar, and Rajan Swami

10. Nanocargos for Efficient Delivery of Nutraceuticals Across Blood-Brain Barrier

Yukta Guggal, Trupti Dandekar, Rajan Swami, and Teenu Sharma

11. Recent Advancement in Strategies for Delivery of Neuronutraceuticals to the Brain

Suman Khurana, Arun Mittal, Parveen Kumar Goyal, Shrestha Sharma, Satish Sardana, Kamica Yadav, and Parul Sood

Biography

Varinder Singh, PhD, is an Assistant Professor of Pharmaceutical Sciences and Technology at Maharaja Ranjit Singh Punjab Technical University, Bathinda, Punjab, India. He is well versed in the fields of natural product chemistry (isolation and characterization of bioactive natural compounds), drug discovery, and pharmacology. He has a strong record of publications in high-impact peer-reviewed journals, with many of his papers cited extensively in the field of natural products.

Amit Kumar, PhD, is an Associate Professor at Chitkara College of Pharmacy, Chitkara University, Punjab, India. He has 12 years of teaching and research experience and has published more than 20 research articles in international journals. He has also filed three patents. His area of research includes neuroprotective drug development and elucidating pathological features of diseases.

Parul Sood, PhD, is an Associate Professor at Chitkara School of Pharmacy, Chitkara University, Himachal Pradesh, India. She has more than 14 years of professional experience in teaching and research. Her area of specialization and research is exploring herbal plants for the treatment of various neurological disorders including, Alzheimer’s disease, as well as pharmacognostical and phytochemical evaluation, and standardization of herbal drugs and herbal drug formulation development.