1st Edition

Neuroplasticity, Development, and Steroid Hormone Action

    432 Pages 60 B/W Illustrations
    by CRC Press

    Neuroplasticity, Development, and Steroid Hormone Action explores the effects of steroid hormones on brain development, function, and aging and is a compilation of cutting-edge research of concern to the disciplines of neurobiology, neuroendocrinology, endocrinology, and developmental biology. The experimental approaches covered range from molecular to behavioral and endocrine to neurobiological. The authors are noted neurobiologists and active researchers from the United States, Japan, and the United Kingdom.

    Divided into five sections and containing scientific photographs, line drawings, tables, color illustrations, and graphs, this interesting and timely text covers the neuroplastic effects of steroid hormones throughout the lifetime of various animal models, such as bees, fish, lizards, turtles, birds, mice, rats, and primates. These sections focus on:
    Ÿ The development and differentiation of neuroendocrine systems
    Ÿ Steroid dependent brain differentiation
    Ÿ The central regulation of hormone secretion
    Ÿ Steroid hormones and neuroplasticity in the mature brain
    Ÿ Steroid mediated mechanisms of cell growth and survival

    Development and Differentiation of the Hypothalamus, Pituitary, and LHRH Neuronal Systems
    Migration of Luteinizing Hormone Releasing Hormone (LHRH) Neurons: The Road to Reproductive Function, S. Wray
    Role of Transcription Factors in the Development of the Hypothalamic Neuronendocrine System, H. Kawano, T. Noda, S. Kimura, and N. Osumi
    Steroid Regulation of Cell Populations in the Insect Central Nervous System,S.E. Fahrbach, K.A. Klukas, and K.A. Mesce
    Molecular Mechanisms of Thyroid Hormone Action in Brain Development, N. Koibuchi
    Positioning Estrogen Receptor Alpha-Containing Cells During Hypothalamic Development, S.A. Tobet, T. Dellovade, K. Parker, and G. Homanics
    The Role of Gluococorticoids and Retinoic Acid in Pituitary Endocrine Cell Differentiation, K. Inoue, H. Goda, C. Mogi, M. Tomida, and S. Tsurugano
    Steroid Dependent Brain Differentiation
    Do Sex Chromosomal Genes Directly Induce Sexually Dimorphic Neural Development, A.P. Arnold, R.J. Agate, L.L. Caruth, M. Patel, W. Perlman, B. Ramachandran, and J. Xu
    Excitatory GABA as a Mediator of Steroid Induced Brain Sexual Differentiation, M.M. McCarthy, T.S. Perrot-Sinal, A.P. Auger, and M.J. Sickel
    Progesterone and Sexual Differentiation of the Developing Brain, C.K. Wagner and P.S. Quadros
    Transient Expression of Estrogen Receptor in the Developing Rat Brain: A Case in the Facial Nucleus, S. Hayashi
    Ontogeny and Molecular Characterization of Estrogen Receptors in the Hippocampus, R.J. Handa, R.H. Price, Jr., C.A. Butler, and D.T. Solum
    Central Regulation of Hormone Secretion
    Hormones, Genes and Pulses: Lessons Learned from Immortalized Cells, M.A. Lawson and P.L. Mellon
    Pulse Generation in LHRH Neurons, E. Terasawa
    A Neuronal Control Circuit for the Gonadotropin-Releasing Hormone Surge in Rats, T. Funabashi, K. Shinohara, and F. Kimura
    Electrical Properteies of Postnatal GnRH Neurons in the Mouse and their Regulation by Gonadal Steroids, A.E. Herbison
    Physiology of GnRH Neurons and Modulation of their Activities by GnRH, Y. Oka and H. Abe
    Electrophysiological Analysis of GnRH Neurons Using a Transgenic Mouse Model, F.E. Dudek, W.A. Pouliot, C. Kuehl-Kovarik, R.A. DeFazio, K.M. Partin, R.J. Handa, and S.M. Moenter
    Steroid Hormones and Neuroplasticity in the Mature Brain
    Novel Estrogen Feedback Associated with Fasting-Induced Suppression of Luteinizing Hormone Secretion in Female Rats, H. Tsukamura, M. Amelita C. Estacio, B.A.S. Reyes, and K. Maeda
    Biochemical, Pharmacological and Functional Characterization of the Corticosterone Membrane Receptor in an Amphibian: A Brief Review, F.L. Moore
    Different Subsets of Preoptic Neurons for Proceptive and Receptive Components of Female Rat Sexual Behavior, Y. Sakuma
    Animal Models of Experiential Effects on Neural Metabolism: Plasticity in Limbic Circuits, J.T. Sakata, A. Gupta, and D. Crews
    In Vivo and In Vitro Studies on Steroid Hormone Receptor and Co-Factors: Tissue Localization in the Brain and Intracellular Dynamics, M. Kawata, M. Nishi, K. Matsuda, H. Ogawa, I. Ochiai, and M. Yoshia
    Differences in Chronic Stress Effects on Cognitive Function in Brain Neurochemistry, V. Luine, K. Beck, R. Bowman, and M. Kneavel
    Steroid Mediated Mechanisms of Cell Growth and Survival
    In Vitro and In Vivo Approaches to the Study of the Neuroprotective Actions of Estradiol, P.M. Wise, M.E. Wilson, D.B. Dubal, and S.W. Rau
    Neuroprotective Effects of Estrogen in Nigral Dopaminergic Neurons. H. Sawada and S. Shimohama
    Novel Cerebellar Function: Neurosteroids in the Purkinje Neurons and their Genomic and Non-Genomic Actions, K. Tsutsui, K. Ukena and H. Sakamoto
    Potential Mechanisms for the Effects of Estrogen on Cognitive Processes: Role of Basal Forebrain Cholinergic Projections, R.B. Gibbs
    Male Reproductive Defects in Puromycin-Sensitive Aminopeptidase Deficient Mice, G.T. Takeuchi

    Short TOC


    Robert J. Handa, Shinji Hayashi, Ei Terasawa, Mitsuhiro Kawata

    "This volume is an outstanding compilation of cutting-edge reports from many of the leading investigators in this field that will catalyze new initiatives in steroid hormone neuroendocrinology... a must-read for every investigator interested in the molecular and systems-level actions of steroid hormones on the brain."
    - James I. Koenig, Ph.D., Maryland Psychiatric Research Center and Secretary, American Neuroendocrine Society