Nicotinic Receptors in the Nervous System  book cover
1st Edition

Nicotinic Receptors in the Nervous System

Edited By

Edward D. Levin

ISBN 9780849323867
Published August 29, 2001 by CRC Press
312 Pages 64 B/W Illustrations

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Book Description

Nicotine research has been conducted for the better part of a century, but with the discovery of the relationship of nicotinic systems to Alzheimer's disease, the differentiation of nicotinic receptor subtypes, and the development of novel nicotinic ligands, the field of nicotine research has exploded. This book will provide you reference to the latest research methods and findings concerning nicotinic neural systems.

Featuring a unique approach, Nicotinic Receptors in the Nervous System provides integrated coverage of cutting-edge research concerning neuronal nicotinic systems relevant to smoking addiction and cognitive dysfunction. By bringing together molecular and neurochemical applications, this book provides the key to understanding function and dysfunction of nicotinic systems and how they are significant for disease, addiction, and the development of novel drug treatments.

Within the next several years, it is very promising that clinical research will support the use of nicotinic treatments for addiction, pain, and cognitive and motor dysfunction. Nicotinic Receptors in the Nervous System provides you with the basic mechanistic background for these treatments as well as the functional assessment necessary to determine therapeutic effects.

Table of Contents

Some Methods for Studies of Nicotinic Acetylcholine Receptor Pharmacology, R.J. Lukas, J.D. Fryer, J.B. Eaton, and C.L. Gentry

Presynaptic Nicotinic Acetylcholine Receptors: Subtypes Mediating Neurotransmitter Release, S. Wonnacott, A. Mogg, A. Bradley, and I.W. Jones
Nicotinic Receptors in the Periphery

Effects of Nicotine on Dopaminergic Neurotransmission, P.P. Rowell

Nicotinic Receptors in the Periphery, S. Jones, H. Lo, and S.A. Simom

Nicotinic Cholinergic Receptors as Targets in Pain Control, M.I. Damaj and C.M. Flores

Mouse Models to Evaluate Genetic Influences on Responses to Nicotine, M.J. Marks and A.C. Collins

Nicotinic Involvement in Cognitive Function in Rats, E.D. Levin and A.H. Rezvani

Nicotine and Cognition in Young and Aged Nonhuman Primates, J.J. Buccafusco and A.V. Terry, Jr.

Evaluation of Pharmacologic Treatments for Smoking Cessation, J.E. Rose

Nicotine and Schizophrenia, J.P. McEvoy

Nicotinic Medications and Tourette's Disorder, R.D. Shytle, A.A. Silver, M. Newman, B.J. Wilkinson, and P.R. Sandberg

Nicotine Effects on Attention Deficit Hyperactivity Disorder, E.D. Levin

Clinical Methodologies in the Examination of Nicotinic Effects, A. Potter and P.A. Newhouse

Nicotinic Systems: An Integrated Approach, E.D. Levin

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"Well known researchers from the Old and New Worlds contributed to this book…presents an integrated approach to nicotine research that should help to identify critical neuropharmacological mechanisms for both adverse and potentially therapeutic effects of nicotine. Edward Levine has contributed much to the development of nicotine research on cognitive functions."
Jacques le Houezec, SRNT Newsletter, October/November 2002