1st Edition

Plant Derived Bioactive Compounds in Human Health and Disease

Edited By Surajit Pathak, Antara Banerjee Copyright 2025
    360 Pages 77 Color & 1 B/W Illustrations
    by CRC Press

    This book comprehensively reviews the diverse role of phytochemicals in promoting human health and combating diseases. The initial chapters introduce phytochemicals, navigate the natural health landscape, and provide a foundational understanding of these bioactive compounds. The book unfolds the role of phytochemicals as a formidable defense against oxidative stress and presents the unique health impacts and nutritional significance of phytochemicals from fruit peels. The chapters further discuss the therapeutic potential of phytochemicals in combating multi-drug-resistant bacterial infections and modulating pathways in inflammation and cancer. It highlights the treatment strategies for amyloidosis using natural products and the intriguing connection between natural compounds and biogenic nanoparticles in polycystic ovarian syndrome (PCOS). The book in turn explores the effects of plant-derived compounds on cancer stem cells and recent advances in ethanopharmacology for age-related brain disorders. This book serves as a comprehensive guide for researchers, practitioners, and students, offering a multidimensional exploration of plant-derived bioactive compounds and their implications for human health and disease. 

    1.    Harnessing nature's richness: Delving into the impact of phytochemicals from fruit peels on health and wellness.

    Koushik.B.R, Seema J Patel, Kishore kumar B, Ganesh G Tilve

    2.    The role of bioactive principle from Traditional medicinal plants in Metabolic Disorder. Shanmuga Priya Murugan1, Kavitha Murugesan1, Yuvarani Muthusamy1, Kanthesh M Basalingappa2, Manohar Murugan3, Nirmala Mahendran1, Priya Rajendran1, Gobianand Kuppannan1 and Malarvizhi Arthanari1

    3.    Phytochemicals as a prospective alternative strategy for combating multi drug resistant bacterial infection.

    Ramachandran Abinaya1, Mangalasamy Jothika1, Kesavaram Padmavathy 2 and Dhandapani Prabu1

    4.    Mechanism of Phytochemicals in modulating signalling pathways involved in Inflammation and Cancer.

    Hemarangan.J1, Yashoda K1, Srisri Satish Karthik 2, Harin N Ganesh2, Vasanth Kanth TL3, Vijay Murali RM3, Shriya P4, Shambhavi Jha4, Kumaran K5, Raksa Arun5, Arul Jothi KN1, * Satish Ramalingam1

    5.    Structure-Activity Relationship of Plant-derived Bioactive compounds in Anti-cancer therapy.

    Pradip Debnatha,b, Vishal Kumar Debc, Sourav Nathd, Anupam Guhae, Suman Adhikarid

    6.    New insights on Anti-colorectal Cancer effects of plant based Bioactive compounds.

    Akshatha S J1, Anusha S N2, Anjani3 and  Mahadesh Prasad A J4

    7.    Evaluation of Nutraceuticals in Targeting Oral Cancer.

    Amirtha Varshinia, Lohapriya K Ba, Jayadevan Poojaa, Arikketh Devia

    8.    Role of Resveratrol in Molecular Targeting of Melanoma.

    Girish Sharma 1,2*, Nishtha Chauhan1, Tanishqua Chopra

    9.    Effects of plant derived compounds against cancer stem cells.

    Rose Mary Stiffin1 Madhumita Das2,3 Jayanta Kumar Das

    10. An Overview of Cardiovascular Disease Management with Plant-Derived Bioactive compounds.

    Diptimayee Das1, Keerthi. N1, Antara Banerjee1, Asim K. Duttaroy2*, Surajit Pathak

    11. Analysis of Phytochemicals – The Free radical warrior in colostrums.

    Rachana R Rao1, Sudipta Choudhury1, Logesh S2 , Gopenath TS2 and Kanthesh M Basalingappa1

    12. Potential Health Benefits Of Phytochemical Compounds On Endocrine Disruption And Female Reproductive Health.

    Barathi Seetharaman1, Akshaya Chandrakanth1, Winkins Santosh2, Ramasamy Vasantharekha1*

    13. Natural Compounds and Biogenic nanoparticals in treatment of Polycystic Ovarian Syndrome.

    Sayani Mondal¥, Akansha Chakraborty¥ and Kousik Pramanick*

    14. The hallmarks of amyloidosis on treatment strategies using natural products.

    Saranya Udayakumar, Agnishwar Girigoswami, Shangavy P, J Jashwanth Raj, Koyeli Girigoswami

    15. Regulation of cell signaling pathways by phytochemicals in aging brain.

    Anushka Agrawal a1, Ankita Panigrahia2, Dhanu AS a3, Gobianath Kb , Malarvizhi Arthanaric and Kanthesh M Basalingappaa4

    16. Recent advances in ethnopharmacology on age related brain disorders.

    Ankita Panigrahi, Anushka Agrawal, Dr. Kanthesh B.M

    17. Anthocyanins and its derivatives: systemic approach in drug delivery.

    Veni Subramanyam1*, Ramakrishnan Ganapathy1, Agiesh Kumar Balakrishna Pillai1, Varsha Virendra Palol1, Haema G2, Indrani Biswas1

    18. Toxic phytochemicals and their potential risks for Human  Health.

    Dr. Winkins Santosh1*, Dr. Ramasamy Vasantharekha2 and Dr. Barathi Seetharaman2, Usha Rani Balu2





    Prof. Surajit Pathak, PhD is currently working as a Professor at Chettinad Academy of Research and Education, Kelambakkam, Chennai (From 2015-till date). He worked as a Principal Research Scientist in Linkoping University, Linkoping, Sweden (2022 May- Dec 2022). He is also a Visiting Professor of Shoolini University, HP and Adjunct Professor at Lovely Professional University, Jalandhar, Punjab. He has received his Ph.D. degree from India in 2007, and completed his Post-Doctoral training (2007-2016) at the University of Alabama, USA, University of Padova, Italy and University of Linkoping, Sweden.

    His current research focuses on role of microRNAs for early detection of colorectal cancer. He has published more than 150 research and review articles in peer-reviewed international journals of repute with 3200 citations and 32 h-index. He serves as an editorial board member for several prestigious international high-impact journals, including "Current Aging Sciences," "Toxics" (MDPI). Dr. Pathak has edited several books of Springer Nature and Elsevier publishers on Stem Cells and Cancer. He is a member of several professional research organizations, including the Indian Association of Cancer Research (IACR), Indian Science Congress Association, Society of Toxicology (SOT), USA, the Aesthetic Multispecialty Society, Europe (AMS) and the ReGenera Research Group in Italy and the Founding member of The Indian Extracellular Vesicles Society (IEVS).

    Dr. Antara Banerjee is presently working as an Associate Professor at Chettinad Academy of Research and Education, Chennai from 2016 till date. Dr. Banerjee pursued her post-doctoral research on Cancer Biology and Regenerative Medicine at University of Padova, Italy and Linkoping University in collaboration, Sweden. These works fostered her interest in understanding the role of the mesenchymal niche and extra-cellular vesicles in tissue regeneration and exploring signaling pathways in governing stem cell fate. Dr Banerjee’s lab is interested in aspects of analyzing the tumor specific microenvironment in colon cancer development including the epigenetic signals as a novel therapeutic strategy.

    She has published over 135 research and review articles in peer reviewed International and National Journals with citation index-2387 and i10-index 54, h-index-24 and has active collaboration with research laboratories in Sweden, Italy, Norway, Turkey, Mexico and India. She has been granted with 2 patent on her research works. She has been awarded with Awarded Young Scientist award by DST SERB, Govt of India. She is the Editor of books with Springer Publishers namely Cancer Stem Cells: New Horizons in Cancer Therapies”; “Handbook of Animal Models and its Uses in Cancer Research” and “Evidence-Based Functional Foods for Prevention of Age-related Diseases”.  She is lifetime member and affiliated with professional research bodies including Indian Association of Cancer Research, Indian Science Congress, Indian society of Extra cellular vesicles.