Practical Systems Biology : Volume 61 book cover
1st Edition

Practical Systems Biology
Volume 61

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ISBN 9780415407809
Published July 31, 2008 by Taylor & Francis
236 Pages 105 B/W Illustrations

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Book Description

Systems biology is the study of organisms as interacting networks of genes, proteins and reactions. Practical Systems Biology provides a detailed overview of the different approaches used in this relatively new discipline, integrating bioinformatics, genomics, proteomics and metabolomics. Various areas of research are also discussed, including the use of computational models of biological processes, and post-genomic research.

Each chapter is written by an experienced researcher and gives an excellent account of various issues of systems biology that is suitable for postgraduate and postdoctoral researchers who are interested in this expanding area of science.


Table of Contents

1. What is Systems Biology and Why Do It?  2. The Circuitry of Circadian Rhythms  3. Intracellular Signalling During Bacterial Chemotaxis  4. Intercellular Signalling and Self-Organisation of Dictyostelium discoideum  5. Modelling the Mammalian Heart  6. Using Mathematical Models to Probe Experimental Data  7. Bioinformatic Approaches to Biological Systems  8. Modelling Tools for Systems Biology and MAPK Cascade Dynamics  9. An Introduction to Metabolic Modelling  10. Vertical Systems Biology: From DNA to Flux and Back  11. Cell Sampling and RNA Amplification Methods  12. Proteomics Methods  13. Towards a Virtual Devleoping Organ 

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University of Bristol, UK