At a point where most introductory organic chemistry texts end, this problems-based workbook picks up the thread to lead students through a graduated set of 120 problems. With extensive detailed spectral data, it contains a variety of problems designed by renowned authors to develop proficiency in organic structure determination.
This workbook leads you from basic problems encountered in introductory organic chemistry textbooks to highly complex natural product-based problems. It presents a concept-based learning platform, introducing key concepts sequentially and reinforcing them with problems that exemplify the complexities and underlying principles that govern each concept.
The book is organized in such a way that allows you to work through the problems in order or in selections according to your experience and desired area of mastery. It also provides access to raw data files online that can be downloaded and used for data manipulation using freeware or commercial software.
With its problem-centered approach, integrated use of online and digital resources, and appendices that include notes and hints, Problems in Organic Structure Determination: A Practical Approach to NMR Spectroscopy is an outstanding resource for training students and professionals in structure determination.
Ancillary materials include:
"This book is a practical introduction to the world of NMR structure elucidation, starting at a level where organic chemistry students will feel comfortable, and finishing off with challenging de novo structure elucidation problems at a level where most organic chemists should be able to improve their skillset."
– Prof. Dr. R. Müller, Managing Director of the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Head of the Department of Microbial Natural Products.
"Drs. Linington, Williams, and MacMillan have combined their considerable talents and resources to produce an extremely well thought-out book containing organic compound structural determination problems of graduated difficulty that will be genuinely useful. It can be very strongly recommended to students and practitioners of various levels of ability."
– Dr. A. Douglas Kinghorn, Professor, and Jack L. Beal, Chair of the College of Pharmacy, The Ohio State University and Editor of Journal of Natural Products.
"Nuclear magnetic resonance spectroscopy (NMR)… covers a wide range of scientific areas from physics to medicine, and no single monograph can cover all of its aspects. Drs. Linington, Williams, and MacMillan provide excellent materials for NMR training through a problem-based learning approach in their new book entitled Problems in Organic Structure Determination, A Practical Approach to NMR Spectroscopy. …
In summary, this informative NMR-based structure elucidation monograph covers most of the NMR tricks that can assist students and professionals solve structures of simple and complex synthetic and natural product molecules. I highly recommend this monograph as an addition to any personal collection and to university libraries."
– H. Liva Rakotondraibe, The Ohio State University, Columbus, Ohio, United States.
"This well-thought repository of NMR spectra of a huge number of organic compounds of varying structural skeletons serves as a practical guide, not only to the organic chemistry students but to the professionals at all levels as well, in developing their understanding and skill. The authors have worked hard in bringing out this excellent book, and it can be strongly recommended to the readers at all levels of ability."
– Prof. Dr. Goutam Brahmachari, Chemistry Department, Visva-Bharati (a Central University), West Bengal, India.
Structure Confirmation for Simple Molecules
Structure Confirmation for Complex Molecules
Determination of Unknown Structures for Simple Molecules
Determination of Unknown Structures for Complex Molecules
Determination of Relative Configurations Using NMR Methods
Complex Unknown Natural Product Structure Determination
Appendix A: NMR Solvent Reference Chemical Shifts
Appendix B: Problem Notes
Appendix C: Problem Hints
Appendix D: Distribution of Experiment Types
Appendix E: Distribution of Functional Groups
Appendix F: Selected 15N NMR Chemical Shifts