Proteoglycans in Lung Disease: 1st Edition (Hardback) book cover

Proteoglycans in Lung Disease

1st Edition

By Hari G. Garg

CRC Press

480 pages

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Hardback: 9780824708153
pub: 2002-10-16
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Description

Discusses new treatment strategies for malignant mesothelioma, pulmonary edema, fibrosis, asthma, emphysema, and bronchiectasis.

Proteoglycans in Lung Disease considers

  • glycosaminoglycans as novel therapeutic agents or targets in lung disease

  • the role of proteoglycans in determining mechanical behavior of lung tissue

  • hyaluronan and its receptors in wound healing, inflammation, vasculogenesis, and angiogenesis

  • the impact of small proteoglycans on matrix assembly

  • versican as a modulator of cell adhesion, migration, and proliferation

  • antiproliferative activity of heparin and its derivatives on pulmonary artery smooth muscle cells

  • the effects of mechanical strain on proteoglycans

  • the functions of proteoglycans in the vascular wall

  • the effect of hypoxia on glycosaminoglycans in the lung

    Comprised of more than 1940 references, Proteoglycans in Lung Disease

  • Table of Contents

    Proteoglycans of the Lung

    Peter J. Roughley

    Hyaluronan in Lung Function: An Overview

    Paul W. Noble

    Morphological Tools for Studying Lung Proteoglycans

    Paulo Sampaio Guitierrez and Vera Demarchi Aiello

    Proteoglycans, Lung Physiology, and Mechanical Strain

    Mara S. Ludwig

    Hyaluronan and Its Receptors in Lung Health and Disease

    Rashmin C. Savani and Horace M. Delisser

    Hyaluronan and Hyaladherin Signaling in the Lung

    Sara Hamilton, Eva A. Turley, and Fu-Sheng Wang

    Hyaluronan in Malignant Mesothelioma

    Anders L. Thylén and Gunnar Martensson

    Matrix Proteoglycans in Development of Pulmonary Edema

    Daniela Negrini, Alberto Passi, Giancarlo de Luca, and Giuseppe Miserocchi

    The Role of Small Proteoglycans in the Formation of Fribrosis

    Gunilla Westergren-Thorsson, Ellen Tufvesson, Erik Eklund, and Anders Malmstrom

    Versican in the Cell Biology of Pulmonary Fibrosis

    Clive R. Roberts

    Decorin in Asthma

    Anthony E. Redington

    Role of Proteoglycans in the Development and Pathogenesis of Emphysema

    Ymke M. Van Der Geld, Jeanette F. M. Van Straaten, Dirkje S. Postma, and Wim Timens

    Proteoglycans in Normal and Pathological Bronchial Mucus

    K. Ramakrishnan Bhaskar

    Vascular Proteoglycans

    Hannu Järveläinen and Thomas N. Wight

    Degradation of Lung Matrix Proteoglycans in Bronchiectasis

    Daisy Kwok Yan Shum and Mary Sau Man Ip

    Effect of Hypoxia on Glycosaminoglycan Synthesis by Lung Cells

    Eleni Papakonstantinou and George Karakiulakis and Michael Roth

    Integrins, Proteoglycans, and Lung Disease

    Jiahua Xu

    Heparin as a Potential Therapeutic Agent to Reverse Vascular Remodeling

    Hari G. Garg, Charles A. Hales, and Robert J. Linhardt

    Author Index

    Subject Index

    About the Series

    Lung Biology in Health and Disease

    Learn more…

    Subject Categories

    BISAC Subject Codes/Headings:
    MED000000
    MEDICAL / General
    MED079000
    MEDICAL / Pulmonary & Thoracic Medicine