1st Edition
Stem Cells: From Basic Research to Therapy, Volume 1 Basic Stem Cell Biology, Tissue Formation during Development, and Model Organisms
The first volume of Stem Cells deals with the fundamental principles that govern embryonic and somatic stem cell biology. Historically, the identification and characterization of such pathways and general rules of stemness occurred during embryonic development and Volume I reflects this with topics spanning cell cycle regulation, epigenetics, and asymmetric cell division in a number of organ systems from planarian to human. Three specific sections discuss i) Basic Stem Cell Biology, ii) Tissue Formation During Development, and iii) Model Organisms with particular emphasis on those more relevant for biomedical research and, thus, leading to the topics addressed in Volume II.
Preface
Gene Nomenclature
The History of Stem Cells
BASIC STEM CELL BIOLOGY
Cell Cycle Regulation of Pluripotent Stem Cells Amar M. Singh and Stephen Dalton
Asymmetric Cell Divisions and Nuclear Migrations of Neural Progenitors: Two Mechanisms that Infl uence
Neurogenesis Paula Alexandre, Jonathan Clarke and Yoichi Kosodo
Epigenetic Regulation of Adult Stem Cells Frank Rosenbauer and Margaret A. Goodell
Hematopoietic Stem Cell Aging and Oxidative Stress June-Won Cheong, Ayako Nakamura-Ishizu, Eriko Nitta and Toshio Suda
Bioelectric Controls of Stem Cell Function Vaibhav P. Pai and Michael Levin
TISSUE FORMATION DURING DEVELOPMENT
Development from the Fertilized Egg to the Three Germ Layers and its Relevance to Signaling and Lineage Commitment of Embryonic Stem Cells Paul W. Burridge and Kenneth R. Boheler
Hematopoiesis During Embryonic Development Rachel Golub, Paulo Vieira and Ana Cumano
Neural Progenitors and Evolution of Mammalian Neocortex Iva Kelava and Wieland B. Huttner
Dynamic Gene Networks in Neural Stem Cell Regulation Ryoichiro Kageyama, Toshiyuki Ohtsuka, Hiromi Shimojo and Itaru Imayoshi
Stem Cells in the Development, Regeneration and Repair of the Retina Thomas A. Reh
Progenitor Cells in Embryonic and Adult Lungs Emily Fox, Michael L. Litvack and Martin Post
Stem Cells During Tooth Development Abigail S. Tucker and Paul T. Sharpe
Liver and Pancreas: Mechanisms of Development and Size Control Ravi Maddipati and Ben Z. Stanger
MODEL ORGANISMS
Developmental Regulation and De Novo Formation of Stem Cells in Plants Erin E. Sparks, Akihiro Imai, Mitsuyasu Hasebe and Philip N. Benfey
Planarian Totipotent Stem Cells Teresa Adell, Francesc Cebrià and Emili Saló
Zebrafi sh in Stem Cell Research Katy L. Lawson and Leonard I. Zon
Deer Antler Stem Cells—New Aspects and Findings Hans J. Rolf and K. Günter Wiese
Genetic Manipulations of Pluripotent Stem Cells Konstantinos Anastassiadis
Index
About the Authors
Color Plate Section
"…covers the basics as well as the development of a variety of tissues with known stem cells/progenitor cells and stem cell models currently being used in the authors' laboratories. …it would be beneficial to those who wish to use a nonrodent model."
—Ellen Mary Andrews, PhD, Midwestern University
