Structural, Biological, and Non-Biological Applications of Schiff Base Metal Complexes  book cover
1st Edition

Structural, Biological, and Non-Biological Applications of Schiff Base Metal Complexes

  • Available for pre-order on April 4, 2023. Item will ship after April 25, 2023
ISBN 9781032271255
April 25, 2023 Forthcoming by CRC Press
256 Pages 66 Color & 168 B/W Illustrations

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Book Description

Coordination compounds have been well-known for their wide variety of applications for over a century, as well as enhancing the researcher’s interest and concern in evaluating their action mechanism. It is certainly one of the most intensely discussed research topics. Coordination compounds involve different metal-ion-ligand phenomenon. The involved metal ions play a significant role in structural association and functioning of several processes in the genetic and metabolism system.

In recent years, Schiff base ligands have gained significant interest and received a keen interest of many researchers. Schiff’s base ligands have been recognized to hold a wide variety of biological and medicinal activities due to the presence of donor atoms. They have proved exceptional pharmalogical actions such as antimicrobial, anti-tuberclosis, antiplatelet, antidiabetic, antiarthritis, antioxidant, anti-inflammatory, anticancer, antiviral, antimalarial, and analgesic. These biologically active Schiff base ligands have also been shown to inhibit enzyme mobilization and, when bound to a metal ion, exhibit enhanced biological activity, making them useful in a number of fields. As a result, metal complexes of Schiff base ligands are gaining popularity due to their unique properties and functionalities. Schiff base complex-based research for educational and industrial purposes is booming, and the number of publications is gradually increasing. Despite these interests, there is currently no detailed book on Schiff base metal complexes that covers the structures, biological activities, and other non-biological perspectives.

This book delves into the structures of Schiff base metal complexes, which are critical in assessing the biological viability of any complex. It also highlights their biological significance in pharma and drug discovery like antibacterial, antifungal, anticancer, anti-inflammatory, anti-arthritis, anti-diabetic, antioxidants, anti-proliferative, antitumor, anticancer, antiviral. The fundamentals of metal complexes are described, as well as an up-to-date outline of developments in synthesis, characterization methods, properties- chemical, thermal, optical, structural, and applications. This book also discusses the other applications of Schiff base metal complexes: as sensor (luminescent, electrochemical, and biosensor), as pigments in dying and paint industries, as photocatalyst to improve the degradation rate.

Features :

  1. This book would be useful for academia, researchers and engineers working in the area of Schiff base and their metal complexes.
  2. This book will give an in-depth account of the properties of Schiff base and their metal complexes.
  3. This book will discuss the details of synthesis methods for Schiff base and their metal complexes.
  4. This book will cover emerging trends in the use of Schiff base metal complexes in the industry.
  5. This book will provide an overview of the wider biological applications of Schiff base metal complexes

Table of Contents

  1. Schiff base metal complexes: Structure and chemical, thermal, optical properties and mechanical structure-property relationships
  2. Therapeutic approaches of Schiff base metal complexes in the treatment of diabetes mellitus
  3. Proliferation inhibition of Schiff base metal complexes
  4. Biologically active Schiff base metal complexes as antibacterial and antifungal agent
  5. Utilization of Schiff base metal complexes as antiviral and anti-parasitic agent
  6. Medicinal activities of anti-inflammatory Schiff base metal complexes
  7. Role of Schiff base metal complexes in the fight against tumors and cancer
  8. Advancement of Schiff base metal complexes interacting with DNA
  9. Schiff base metal complexes in nano-medicines
  10. Schiff base metal complexes-based sensors for application
  11. State of the art and future perspective of Schiff base metal complexes in biological treatment
  12. Molecular docking and drug design of Schiff base metal complexes

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Dr. Pallavi Jain

Dr. Pallavi Jain has a very luminous academic and professional career. She is currently working as Associate Professor in the Department of Chemistry, SRM Institute of Science and Technology Delhi-NCR Campus, Modinagar, Ghaziabad, India. Dr. Jain received her Ph.D. degrees in Chemistry from Banasthali Vidyapith, Rajasthan, India in 2017. She has extensive teaching experience of about 16 years. Her research interest focuses on the development of transition metal complexes incorporating Schiff base ligands for their biological importance in drug delivery. Her research interests also focus on the synthesis of metal complexes as effective biosensors. She has authored and co-authored over 45 publications in journals of international repute, and contributed more than a dozen of book chapters.

Dr. Prashant Singh

Dr. Prashant Singh done M.Sc. in Chemistry from Indian Institute of Technology, Delhi in 2005. After completion, he joined the research group of late Dr. N. N. Ghosh, at Dr. B. R. Ambedkar Centre for Biomedical Research, University of Delhi, India. He received his Ph.D. in January, 2010. He obtained the position of Assistant Professor at Atma Ram Sanatan Dharma (ARSD) College, University of Delhi in 2006 and published about 100 research articles/ reviews/ chapters in journals of international repute. Citation of his work is more than 1500. He is awarded with UGC postdoctoral research fellowship and also offered for post-doctoral fellowship from North-West University, South-Africa.