1st Edition
The Dynamic Nature of Mitochondria from Ultrastructure to Health and Disease
I. Mitochondrial ultrastructure – molecular mechanisms shaping the inner membrane
1. Roles of the F1FO-ATP synthase and MICOS in mitochondrial membrane organization
Patrick Horten & Heike Rampelt
2. Proteolytic regulation of mitochondrial architecture
Gunjan Purohit & Oleh Khalimonchuk
II. Mitochondrial cristae and lipid dynamics: from super-resolution microscopy to lipid-OXPHOS interplay
3. Changes in cristae architecture and function: from static to dynamic
Ruchika Anand & Arun Kondadi
4. Emerging roles of phospholipids in the structure and function of the Oxidative Phosphorylation complexes
Nanami Senoo & Steven Claypool
5. Mitochondrial Hydrogen Peroxide Dynamics
Jan Riemer and Helmut Sies
6. Mitochondria-lysosome crosstalk, in disease and in health
Carla Lopes & Nuno Raimundo
IV. Mitochondria in health and disease: from mtDNA release to Complex I assembly
7. mtDNA in & out - On the tightrope of cellular health
Andrea Irazoki & David Pla-Martín
8. Mitochondrial Complex I Assembly and Implications for Mitochondrial Disease
Luke Formosa
V. Advanced methods in mitochondrial biology and metabolism research
9. The optogenetic landscape of the mitochondrion
Odette Deen-Rozalen, Marius Nieke, Sara Shumka, Hannes M. Beyer, and Matias D. Zurbriggen
VI. Integrative view on mitochondrial research and outlook
10. Mitochondrial biology – – a vibrating and dynamic research field still breaking boundaries
Andreas Reichert
Biography
Andreas S. Reichert has been a Professor and Director of the Institute of Biochemistry and Molecular Biology I at the Heinrich-Heine University Düsseldorf, Germany since 2014. He’s been a board member of the Biologisch-Medizinisches Forschungszentrum (BMFZ) at Heinrich-Heine University Düsseldorf, Germany since 2016, and a speaker of BMFZ since 2021. Dr. Reichert received his Ph.D. under Prof. Dr. Svante Pääbo at the Institute of Zoology, Ludwig-Maximilians-Universität München, Germany in 1999, and was a Post-Doc under Prof. Dr. Svante Pääbo and Prof. Dr. Mario Mörl at the Max Planck Institute for Evolutionary Anthropology, in Leipzig, Germany from 1999-2000. As the Executive Director of the Center for Membrane Proteomics (CMP) at Goethe University Frankfurt am Main, from 2012-2014, Dr. Reichert simultaneously operated as a professor and Head of Mitochondrial Biology at Goethe University Frankfurt am Main, Germany.
