Oxidative stress is an underlying factor in health and disease. In this series of books, the importance of oxidative stress and disease associated with organ systems is highlighted by exploring the scientific evidence and the clinical applications of this knowledge. This series is intended for researchers in the basic biomedical sciences and clinicians.
Open Access makes published academic research freely and permanently available online for anyone, anywhere. OA publications are downloaded 7 times more often, cited 50% more, and mentioned online 10 times more often. Upon publication, OA content is made available in digital format to read and download under a Creative Commons license.
Options are available to editors, authors and contributors to the series. See https://www.routledge.com/our-products/open-access-books/taylor-francis-oa-books for more information and frequently asked questions with respect to these options or contact Chuck Crumly, Senior Acquisitions Editor, at [email protected] for more details.
Oxidative Eustress in Exercise Physiology
Proteostasis and Proteolysis
Cancer and Vitamin C
The Biology of the First 1,000 Days
Biomedical Application of Nanoparticles
By André Kleinridders
September 06, 2022
The brain is crucial for the regulation of whole-body metabolism and behavior. The pancreas-derived hormone insulin modulates brain function and affects energy metabolism as well as cognition. This is partially achieved by modulating several types of brain cell populations including those relevant ...
By James N. Cobley, Gareth W. Davison
June 10, 2022
Oxidative Eustress in Exercise Physiology unravels key physiological responses and adaptations to different redox-regulated exercise paradigms at the cell, tissue, and whole-body level in model systems and humans in health and disease. While the mechanistic details are still unclear, key ...
By Niki Chondrogianni, Elah Pick, Anna Gioran
December 03, 2021
Proteostasis integrates biological pathways controlling biogenesis, trafficking, folding, and degradation of proteins. This book focuses on two protein breakdown/degradation processes (proteolysis), which are part of a normally functioning proteostatic system: the ubiquitin-proteasome system and ...
By Carsten Berndt, Christopher Horst Lillig
October 18, 2021
Cell differentiation and the development of multicellular organisms are processes of self-assembly, controlled and driven by signaling molecules and cascades including redox regulation. These reactions may have provided the energy for the first metabolic steps in the evolution of life. Today, redox...
By Clare Hawkins, William M Nauseef
October 08, 2021
Mammalian heme peroxidase enzymes play a critical role in innate immune responses and disease prevention. The formation of potent chemical oxidants is essential to this protective physiologic activity in immunity. Although highly beneficial in the context of immune defense, it is now well ...
By Qi Chen, Margreet C M Vissers
February 10, 2020
Vitamin C may offer significant therapeutic benefits in the treatment of cancer. This book includes chapters by a group of leading scientific researchers documenting the ways cancer can be affected by high doses of ascorbate. After an initial chapter providing a historical perspective, subsequent ...
By Qi Chen, Margreet C M Vissers
February 03, 2020
Vitamin C holds a unique place in scientific and cultural history. In this book, a group of leading scientific researchers describe new insights into the myriad ways vitamin C is employed during normal physiological functioning. In addition, the text provides an extensive overview of the following:...
By Leopold Flohe
October 08, 2018
This is the first serious attempt to synthesize all that became known of glutathione over the last three decades. The book contains an update of glutathione biosynthesis with special emphasis on its regulation in adaptive stress responses. Other chapters review glutathione transport systems and ...
By Margreet C M Vissers, Mark Hampton, Anthony J. Kettle
October 16, 2017
Much of the biology of oxidative stress and oxidative signalling centres on the generation and handling of hydrogen peroxide. The overall aim for this book would be to provide an insightful and useful forum to assist with the understanding of the relevance of hydrogen peroxide generation and how ...
By Crystal D Karakochuk, Kyly C. Whitfield, Tim J Green, Klaus Kraemer
September 20, 2017
The first 1,000 days, from conception to two years of age, is a critical period of growth and development. Exposures to dietary, environmental, hormonal, and other stressors during this window have been associated with an increased risk of poor health outcomes, some of which are irreversible. The ...
By Bertrand Henri Rihn
September 07, 2017
Biomedical Application of Nanoparticles explores nanoparticles, their chemical and physicals properties, and how they interact in biological systems with proteins, immune system and targeted cells. Risk assessment of nanoparticles for human is described, including: cellular paradigms, ...
By Mulchand S. Patel, Jens H. Nielsen
June 16, 2017
There is a documented link between fetal nutrition and the development of disease risk in adult life. Including the early postnatal period, during which a newborn continues to grow rapidly influenced by environmental factors, suggests that individuals are subject to risks for more than just the ...