Oxidative stress is an underlying factor in health and disease. In this series of books, the importance of oxidative stress and disease associated with organ systems is highlighted by exploring the scientific evidence and the clinical applications of this knowledge. This series is intended for researchers in the basic biomedical sciences and clinicians.
Open Access makes published academic research freely and permanently available online for anyone, anywhere. OA publications are downloaded 7 times more often, cited 50% more, and mentioned online 10 times more often. Upon publication, OA content is made available in digital format to read and download under a Creative Commons license.
Options are available to editors, authors and contributors to the series. See https://www.routledge.com/our-products/open-access-books/taylor-francis-oa-books for more information and frequently asked questions with respect to these options or contact Chuck Crumly, Senior Acquisitions Editor, at [email protected] for more details.
Edited
By Andreas S. Reichert
April 15, 2024
Mitochondrial research has exploded over the last ~150 years. This book gives an amazing view on a conceptual change in our understanding of mitochondrial biology. It becomes clear that mitochondria are extremely dynamic in nature controlling life at multiple levels. Mitochondria rule energy ...
Edited
By Clare Hawkins, William M Nauseef
January 29, 2024
Mammalian heme peroxidase enzymes play a critical role in innate immune responses and disease prevention. The formation of potent chemical oxidants is essential to this protective physiologic activity in immunity. Although highly beneficial in the context of immune defense, it is now well ...
Edited
By Niki Chondrogianni, Elah Pick, Anna Gioran
January 29, 2024
Proteostasis integrates biological pathways controlling biogenesis, trafficking, folding, and degradation of proteins. This book focuses on two protein breakdown/degradation processes (proteolysis), which are part of a normally functioning proteostatic system: the ubiquitin-proteasome system and ...
Edited
By Carsten Berndt, Christopher Lillig
January 29, 2024
Cell differentiation and the development of multicellular organisms are processes of self-assembly, controlled and driven by signaling molecules and cascades including redox regulation. These reactions may have provided the energy for the first metabolic steps in the evolution of life. Today, redox...
Edited
By Giuseppe Valacchi, Andreas Daiber
December 15, 2023
Environmental risk factors – noise, air pollution, chemical agents, and ultraviolet radiation – impact human health by contributing to the onset and progression of noncommunicable diseases. Accordingly, there is need for preclinical and clinical studies and comprehensive summary of major ...
Edited
By Iria Medraño-Fernandez, Gerd Patrick Bienert, Roberto Sitia
October 11, 2023
To produce energy, aerobic organisms transform oxygen molecules into water. This reductive mechanism yields toxic radical intermediates, collectively known as reactive oxygen species (ROS). Paradoxically, these physiological processes entail the production of potentially damaging species. Evolution...
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By André Kleinridders
September 06, 2022
The brain is crucial for the regulation of whole-body metabolism and behavior. The pancreas-derived hormone insulin modulates brain function and affects energy metabolism as well as cognition. This is partially achieved by modulating several types of brain cell populations including those relevant ...
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By James N. Cobley, Gareth W. Davison
June 10, 2022
Oxidative Eustress in Exercise Physiology unravels key physiological responses and adaptations to different redox-regulated exercise paradigms at the cell, tissue, and whole-body level in model systems and humans in health and disease. While the mechanistic details are still unclear, key ...
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By Qi Chen, Margreet C M Vissers
February 10, 2020
Vitamin C may offer significant therapeutic benefits in the treatment of cancer. This book includes chapters by a group of leading scientific researchers documenting the ways cancer can be affected by high doses of ascorbate. After an initial chapter providing a historical perspective, subsequent ...
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By Qi Chen, Margreet C M Vissers
February 03, 2020
Vitamin C holds a unique place in scientific and cultural history. In this book, a group of leading scientific researchers describe new insights into the myriad ways vitamin C is employed during normal physiological functioning. In addition, the text provides an extensive overview of the following:...
Edited
By Leopold Flohe
October 08, 2018
This is the first serious attempt to synthesize all that became known of glutathione over the last three decades. The book contains an update of glutathione biosynthesis with special emphasis on its regulation in adaptive stress responses. Other chapters review glutathione transport systems and ...
Edited
By Margreet C M Vissers, Mark Hampton, Anthony J. Kettle
October 16, 2017
Much of the biology of oxidative stress and oxidative signalling centres on the generation and handling of hydrogen peroxide. The overall aim for this book would be to provide an insightful and useful forum to assist with the understanding of the relevance of hydrogen peroxide generation and how ...