Toxins and Biologically Active Compounds from Microalgae, Volume 2 : Biological Effects and Risk Management book cover
1st Edition

Toxins and Biologically Active Compounds from Microalgae, Volume 2
Biological Effects and Risk Management

Edited By

Gian Paolo Rossini

ISBN 9781482231465
Published April 24, 2014 by CRC Press
700 Pages 13 Color & 63 B/W Illustrations

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Book Description

Toxins and Biologically Active Compounds from Microalgae: Volume 2: Biological Effects and Risk Management  is devoted to the effects toxic microalgae and their poisonous products exert on living systems and how they may affect human activities. The most advanced information regarding the molecular mechanisms of action of major groups of toxins is presented, to frame for the description of toxic responses found in living systems exposed to microalgal toxins. Accounts of the recognized environmental effects of harmful algal blooms and the existing therapeutic applications of some toxins have been included.

The picture is completed by the description of current initiatives to manage the risks posed by toxic microalgae, including strategies for the detoxification of contaminated seafood and the efforts to use most advanced informatic tools for the development of models for robust predictions regarding the appearance and the dynamics of harmful algal blooms. The complexity of risk management in the field is presented from a global perspective by highlighting major issues approached in world regions whose economic importance with regard to the production and commercialization of seafood is undeniable.

Table of Contents

Molecular Mechanisms and Modes of Action of Microalgal Toxins
The Mechanism of Action Of Microalgal Toxins Interacting with NaV and KV Channels
Pharmacological Actions of Palytoxin
Molecular Mechanisms of Maitotoxin Action
The Mechanisms of Action of Domoic Acid: From Pathology to Physiology
Cyclic Imine Neurotoxins Acting on Muscarinic and Nicotinic Acetylcholine Receptors
Molecular Bases of Effects of Azaspiracids and Yessotoxins
Proteomic Tools to Elucidate the Molecular Action of Micro‐Algal Toxins

Impact of Toxic Microalgae and Microalgal Toxins on Biological Systems
Domoic Acid: Biological Effects and Health Implications
Toxicity of Okadaic Acid/Dinophysistoxins and Microcystins on Biological Systems
Toxicity of Cyclic Imines
Clinical Applications of Paralytic Shellfish Poisoning Toxins
Toxicology of Ciguatoxins
Toxicity of Palytoxins: From Cellular to Organism Level Responses
Effects of Toxic Microalgae on Marine Organisms

Management of Risks Posed by Toxic Microalgae and Microalgal Toxins
Phycotoxins: Seafood Contamination, Detoxification and Processing
Coupled Nature‐Human (CNH) Systems: Generic Aspects of Human Interactions with Blooms of Florida Red Tide (Karenia brevis) and Implications for Policy Responses
Modeling of Harmful Algal Blooms: Advances in the Last Decade
Challenging Times for the Detection of Marine Biotoxins in the EU
Risk Management of Marine Algal Toxins in China
Some Models of Risk Management Posed by Toxic Microalgae and Microalgal Toxins in Africa
International Initiatives to Assess and Manage the Risk of Biotoxins in Bivalve Molluscs

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