Understanding Lipid Metabolism with Microarrays and Other Omic Approaches: 1st Edition (Hardback) book cover

Understanding Lipid Metabolism with Microarrays and Other Omic Approaches

1st Edition

Edited by Alvin Berger, Matthew A. Roberts

CRC Press

472 pages

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Hardback: 9780824758110
pub: 2004-11-30
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Description

Reviewing current studies and previously unpublished research from leading laboratories around the world, Unraveling Lipid Metabolism with Microarrays demonstrates the use of microarrays and transcriptomic approaches to clarify the biological function of lipids. With contributions from world-class researchers, the book focuses on the use of microarrays to study and understand lipid metabolism.

With coverage that spans the technologies of genomics, transriptomics, and meatabolomics, the text contains reviews of published work, provides a fresh look at new data, and presents previously unpublished work. It explores the role of fatty acids in gene expression and the various effects lipids have on the cell cycle, cholesterol metabolism, and insulin secretion. Taking a proteomic approach to looking at lipids, the book covers a wide variety of subjects, all linked to the study of lipid metabolism.

Reviews

"There are many tables, cartoons and references up to 2003. Who is not interested in the role of lipids, in obesity, diabetes, cardiovascular degree, etc and modern basic research?"

-Pediatric Endocrinology Reviews

Table of Contents

DATA ANALYSIS AND STATISTICAL INTERPRETATION IN MICROARRAY EXPERIMENTS

Statistical Design and Data Analysis for Microarray Experiments, D.R. Golstein and M. Delorenzi

EXPLORING FATTY ACID AND CHOLESTEROL METABOLISM USING MICROARRAYS

Dietary Effects of Arachidonate-Rich Fungal Oil and Fish Oil on Murine Hepatic Gene Expression: Focus on Newly Described LC-PUFA Regulated Genes, A. Berger and M.A. Roberts

Dietary Effects of Arachidonate-Rich Fungal Oil and Fish Oil on Murine Hippocampal Gene Expression: Links to Transcription Factors and Behavior, A. Berger and M.A. Roberts

Exploring the Effects of Polyunsaturated Fatty Acids on Gene Expression in Human Hepatocyte (HepG2 Cells) Using DNA Chip, Y. Fujuwara and A. Masumoto

Neurological Effects of Dietary N-3 Fatty Acids in Rat Brain, T. Farkas, K. Kitajka. G. Barcelo-Coblijn, and L.G. Puskas

Anterior and Posterior Cerebral Gene Expression in a Rat Model of Reduced Brain Docosahexaenoic Acid During Development, J.B. Gaines, N.E.J. Berman, S.E. Carlson

A Genomic Approach to Studying Leptin Signaling in a Hypothalmic Cell Line, W. Kaszubska, P. Hessler, and P.E. Kroeger

Characterizing Cholesterol Metabolism in Atherosclerosis Susceptible and Resistant Mouse Models Using DNA Microarrays, L. Vergnes, J. Phan, and K. Reue

Microarray Analysis of Lipid Metabolism in Drug Abuse, Neurological and Psychiatric Disorders, E. Lehrmann, C.-T. Lee, J. Chen, K.G. Becker, and W.J. Freed

EXPLORING THE ROLES OF PPARS, HNFS, AND SREBPS USING MICROARRAYS

Microarray Analyses of SREBP-1 Target Genes, N. Yahagi and H. Shimano

Understanding the Coordinated Effects of PPARs on Lipid Metabolism Using Microarrays, S. Kersten, P. Escher, S. Tafuri, and W. Wahli

Microarray Analysis of Changes Induced by Peroxisome Proliferator-Activated Receptor a-Agonists in the Expression of Genes Involved in Lipid Metabolism, K. Yamazaki, T. Hihara, H. Yoshitomi, J. Kuromitsu, and I. Tanaka

EXPLORING LIPIDS AND CARCINOGENESIS USING MICROARRAYS

How Dietary Long Chain Fatty Acids Induce Gene Signals Involved in Carcinogenesis, P. Anderle, P. Farmer, A. Berger, and M.A. Roberts

Omega-3 Polyunsaturated Fatty Acid Against Colon Cancer: DNA Microarray Analysis of Gene-Nutrient Interactions, B.A. Narayanan, N.K. Narayanan, and B.S. Reddy

Ellagic Acid Modulate Lipid Metabolism in Prostate Cancer: Gene-Nutrient Interactions, B.A. Narayanan, N.K. Narayanan, O. Geoffrey, and D.W. Nixon

EXPLORING HOW LIPIDS AFFECT INSULIN SECRETION USING MICROARRAYS

Changes of Gene Expression in INS-1 Cells: The Implication of Pamitate in Lipotoxicity, J.Xiao, M. Kruhoffer, P. Bendix Jeppesen, A. Reziwanggu, T. Orntoft, and K. Hermansen

Use of Microarrays to Investigate the Transcriptional Effects of Protein Tyrosine Phosphatase IB (PTP1B): Implications for Diabetes and Obesity, C.M. Rondinone and J.F. Waring

OTHER "OMIC" TECHNIQUES FOR UNRAVELLING LIPID METABOLISM

Metabonomics as a Tool for Understanding Lipid Metabolism, D.J. Grainger, D.E. Mosedale, E. Holmes, and J.K. Nicholson

Zebrafish Model of Lipid Metabolism for Drug Discover, A.L. Rubinstein, S.-Y. Ho, and S.A. Farber

Subject Categories

BISAC Subject Codes/Headings:
MED008000
MEDICAL / Biochemistry
SCI029000
SCIENCE / Life Sciences / Genetics & Genomics
TEC012000
TECHNOLOGY & ENGINEERING / Food Science