A Guide to Pharmaceutical Particulate Science  book cover
1st Edition

A Guide to Pharmaceutical Particulate Science

ISBN 9781574911428
Published March 12, 2003 by CRC Press
256 Pages 19 B/W Illustrations

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Book Description

The pharmaceutical applications of powder technology have long been recognized. Yet while many books focus on aspects of powder formation and behavior, there has been no text that explores the power of particulate science in the design, manufacture, and control of quality medicines. Until now. A Guide to Pharmaceutical Particulate Science discusses key principles of particulate science and their practical applications.

The authors cover particulate material, its form and production, sampling from bodies of powder, particle size descriptors and statistics, behavior of particles, instrumental analysis, particle size measurement and synergy of adopted techniques, physical behavior of a powder, and in vitro and in vivo performance criteria. They draw the components of particulate science into a single concise description of their current and potential uses in product development. Exploring the growth in knowledge of particle properties and the variety of technological advances in particle manufacture, A Guide to Pharmaceutical Particulate Science gives readers the tools they need to grasp the science and its use in the industry.

Table of Contents

Introduction and Overview. Particulate Systems: Manufacture and Characterization. Sampling and Measurement Biases. Particle Size Descriptions and Statistics. Behavior of Particles. Instrumental Analysis. Methods of Particle Size Measurement and Their Importance for Specific Applications (Instrument Synergy). Particle Size Behavior and Physical Behavior of a Powder. Clinical Effect of Pharmaceutical Particulate Systems. General Conclusions. References. Index.

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"[This book] treats … various topics … in a logical sequence. The references are extensive and provide the reader with valuable guidance to the relevant literature, especially in the pharmaceutical sciences. … [T]his book provides an excellent foundation for a didactic course in particulate science or powder technology. … [It] will likewise be valuable to scientists who are eager to acquire basic knowledge of particulate science in pharmaceutics."
- Pharmaceutical Research

"A useful guide to the subject…the volume covers a gap in the existing literature and should be on the shelves of company libraries."
- Organic Process Research and Development Journal