Alcohol, Drugs of Abuse, and Immune Functions: 1st Edition (Hardback) book cover

Alcohol, Drugs of Abuse, and Immune Functions

1st Edition

Edited by Ronald R. Watson

CRC Press

288 pages

Purchasing Options:$ = USD
Hardback: 9780849383120
pub: 1995-05-04
SAVE ~$86.00
Currently out of stock

FREE Standard Shipping!


Substance abusers are an immunocompromised population, vulnerable to a wide array of new and resurgent infectious diseases - in spite of modern treatment. For example, opportunistic infections like tuberculosis are the principal cause of morbidity and mortality in HIV positive patients. Alcohol- and drug-induced disorders are wide-ranging, gaining prominence as the spectrum of emerging diseases broadens.

Alcohol, Drugs of Abuse, and Immune Functions reviews the role of these immunosuppressants as cofactors in disease. It covers the basic biology and immunology of impairments to defense against infectious disease. Alcohol and drug use is consistently associated with immunosuppression, although it isn't known if it is the substance itself, a metabolite, or an indirect effect that alters disease resistance. This text explores the advances toward answering this question, examines alcohol in different settings, its relationship to important cells, and the effects it can have on vital organs such as the liver and the lungs.

Table of Contents

Immunomodulation Associated with Depression and Stress, E.M. Levy and C. Chancellor-Freeland

The Effect of Alcohol on the Cellular Immune Function in Animals, C.J. Grossman, G. Roselle, and M. Nienaber

Immunomodulation by Alcohol in Mice, S.K. Ardestani and R.R. Watson

Alcohol and Infections of the Lung, G.A. Roselle, C.J. Grossman, M.A. Neinaber, and C.L. Mendenhall

T Cell Modulations in Human Alcoholics, R.T. Cook

Alcoholic Liver Disease, Malnutrition, and the Immune Response, A. Chedid

Modulation of Cytokine Production in Human Lymphoid and Myeloid Cells by Alcohol In Vitro, G. Szabo, P. Mandrekar, B. Verma, and D. Catalano

Alcohol, Endothelial Cells, and Immunity, P. Borgs, M.H. Witte, and C.L. Witte

Effect of Prenatal Alcohol Exposure on Hypothalamic-Pituitary-Adrenal Function and Expression of Glucocorticoid-Regulated Genes, E. Redei, I. Halasz, and F. Aird

Alcohol Metabolism and Its Toxicity: Role of Kupffer Cells and Free Radicals, R.G. Thurman, B.U. Bradford, K.T. Knecht, H.D. Connor, R.P. Mason, U. Adachi, M. Goto, C. Sullivan, and D.T. Forman

Do Alcohol and Other Substances of Abuse Alter the Natural Evolution and Susceptibility to Human Immunodeficiency Virus-1 Infections? O. Bagastra, R.J. Pomerantz, and A. Kajdacsa-Balla

Alcohol and ImmunomodulationDuring Murine Acquired Immunodeficiency Syndrome, Y. Wang, D.S. Huang, and R.R. Watson

Dysregulation in Cytokine Production by Alcohol Consumption: A Cofactor in the Development of Murine Acquired Immunodeficiency Syndrome, Y. Wang and R.R. Watson

Alcohol Abuse as a Possible Cofactor in the Progression of Acquired Immune Deficiency Syndrome: Do Th-1 and Th-2 Helper T Cell Subsets Play a Role? D.A. Cohen

The Role of Alcohol on Endocrine-Immune Interactions, Y. Wang and R.R. Watson

Effects of Cocaine on Certain Macrophage Functions, S.S. Lefkowitz, A. Vaz, and D.L. Lefkowitz

About the Series

Physiology of Substance Abuse

Learn more…

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Immunology
MEDICAL / Pharmacy
MEDICAL / Toxicology