1st Edition
Antimicrobials in Pharmaceutical and Medicinal Research
The need for state-of-the-art antimicrobial agents is greater than ever because of the development of multidrug resistance in communal pathogens, the rapid rise of new infections, and the potential for use of multidrug-resistant agents in biological protection. Although the need for novel antimicrobials is increasing, the development of such agents faces significant obstacles. Pharmaceutical research and development costs are estimated to be $400–$800 million per approved agent. The most important natural antimicrobial compounds derived from various plant sources containing a wide variety of secondary metabolites. With collected contributions from international subject experts, this volume focuses primarily on antimicrobials.
This book deliberates recent developments in microbial science in combating infectious diseases and explores advances in antimicrobial constituents and their applications in the fight against bacteria. In addition, it also provides a variety of photographs, diagrams, and tables to help illustrate the material. The novel strategies to combat antimicrobial resistance are also described, emphasizing collaborative measures of control. We describe the concerted efforts undertaken by global communities to combat antimicrobial resistance in detail. The most efficient strategy could be a behavioural change towards indiscriminate consumption, usage, and prescription of antibiotics.
Students, research scientists, academicians and policy makers can benefit from Antimicrobials in Pharmaceutical and Medicinal Research as a resource that addresses biotechnology, applied microbiology, healthcare/pharmaceutical products, medicinal plant products, and all disciplines related to antimicrobial research.
Features of the book:
- Covers development in plant-based antimicrobials for sepsis management and progress
- Describes modern approaches for phyto-nanoconjugates in combating multidrug resistance in biomedicine
- Details methods to improve antimicrobial properties to have a longer service life in combating infection
- Describe bacteriocins and plant metabolites as biotechnological tools in food, pharmaceuticals and therapeutics applications
- Highlights natural antimicrobial therapeutic peptides
- Offers current and future applications of emerging antimicrobial technologies
1. Antimicrobial cryogels for biomedical use Işık Perçin, Gülşen Bayrak, Ayşe Feyza Keleş, Adil Denizli
2. Natural antimicrobial therapeutic peptides: milk lactoferricin and Spirulina platensis peptides Nawal Abd El-Baky and Amro Abd Al Fattah Amara
3. Plant-Based Antimicrobials for Sepsis Management: What progress have we made? Shikha Joon, Enty Tjoa, Rajeev K. Singla, Rakesh Bhatnagar, Bairong Shen
4. Antimicrobials: Advances in Pharmaceutical and Medicinal Research Rahul Sharma, Himani Meena, Lipsa Panda and Ajit Ramesh Sawant
5. Phyto-Nanoconjugates in combating Multidrug Resistance in Medical Research Charu Gupta and Dhan Prakash
6. Essential Oil Components: Anti-viral Properties Ashwini Khanderao Jadhav, Sankunny Mohan Karuppayil
7. Antimicrobials for sepsis management-Where do we stand? Shikha Joon, Enty Tjoa, Mohit Mishra, Akash Tripathi Ssatsangi, Ketan Parmar, Rakesh Bhatnagar
8. Bacteriocins as Biotechnological tools in food and pharmaceuticals: Applications and future prospects Praveen N, Arpita Jayan, Nithya S, Udisha Singh, BaraiyaDivyeksha Harishchandra, Vasantha V L, Al-Khayri J M
9. Plant-Based Metabolites as Source of Antimicrobial Therapeutics: Prospects and Challenges Praveen N, Preetha R T, Vishakha Pagare, Jyothis Devasia, Aatika Nizam, Epsita Mukherjee, Vasantha V L, Al-Khayri JM
10. New alternatives of treatment against intestinal parasite infection Lissethe Palomo-Ligas, José Roberto Vargas-Villanueva, Mariana Garza-Ontiveros Filiberto Gutiérrez-Gutiérrez, Rocio Guadalupe Castillo-Godina, Lizeth Guadalupe Campos-Muzquiz, Adriana Carolina Flores-Gallegos, Raúl Rodríguez Herrera, Sendar Daniel Nery-Flores
Index
Biography
Arti Gupta obtained her Ph.D. from Mahatma Jyotiba Phule Rohilkhand University, Bareilly, India in 2010 in Animal Science. Dr. Gupta’s current research interests are Animal Biotechnology, Molecular Plant Biotechnology, Molecular Animal Biotechnology, Bioprocess Technology, and Microbiology. Since July 2014, Dr. Gupta has served for Sri Avadh Raj Singh Smarak Degree College, Gonda, Uttar Pradesh, India and engaged in some editorial work with Springer Nature. Dr. Gupta has 10 years of teaching and research experiences in Plant and Animal Biotechnology and Microbial Biotechnology. She has been awarded the University Topper (Gold Medal), M.Sc. (Biotech.) from Ch.C.S.University, Meerut, the Young Scientist Award (Gold Medal) awarded by the Zoological Society of India, Lucknow, Best Poster Presenter awarded by the Asian Journal of Experimental Science, Jaipur, Best Poster Presenter awarded by the International Consortium of Contemporary Biologists (ICCB) and Madhawai-Shyam Educational Trust, Ranchi, the Fellowship Award awarded by the International Consortium of Contemporary Biologists (FICCB) and Madhawi Shayam Educational Trust (FMSET) and Dr. V.P. Agarwal (Gold Medal) awarded by D.A.V. (P.G.) College, Muzaffarnagar. To date she has published a monograph, contributed seven book chapters, published around 50 national and international research papers, edited seven books, and issued 28 abstracts, as well as attending symposia, seminars, conferences, and workshops. Dr. Gupta has lifetime membership of Indian Science Congress Association, the Biotech Research Society of India, the Zoological Society of India and the International Consortium of Contemporary Biologists. She has served as a member on several editorial boards. Previously, she served as Teaching Personnel, G.B. Pantnagar University, Pantnagar, Uttrakhand, India, and Visiting Academic Researcher, BAMRC, SRUC, University of Edinburgh, Scotland.
Dr Ram Prasad, Ph.D. is associated with the Department of Botany, Mahatma Gandhi Central University, Motihari, Bihar, India. His research interests include applied and environmental microbiology, plant-microbe interactions, sustainable agriculture and nanobiotechnology. Dr. Prasad has more than two hundred publications to his credit, including research papers, review articles and book chapters and six patents issued or pending. He has also edited or authored several books. He has twelve years of teaching experience and has been awarded the Young Scientist Award and the Prof. J.S. Datta Munshi Gold Medal by the International Society for Ecological Communications; FSAB fellowship by the Society for Applied Biotechnology; the American Cancer Society UICC International Fellowship for Beginning Investigators, USA; Outstanding Scientist Award in the field of Microbiology; BRICPL Science Investigator Award and Research Excellence Award, to list a few. He has served on several editorial boards. Previously, he served as Assistant Professor at Amity University, Uttar Pradesh, India; Visiting Assistant Professor, Whiting School of Engineering, Department of Mechanical Engineering at Johns Hopkins University, Baltimore, United States; and Research Associate Professor at the School of Environmental Science and Engineering, Sun Yat-sen University, Guangzhou, China.
