Circadian Physiology: 3rd Edition (Hardback) book cover

Circadian Physiology

3rd Edition

By Roberto Refinetti, PhD.

CRC Press

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pub: 2016-04-11
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Description

Circadian rhythms influence most of our life activities, notably getting up and going to sleep every day. This new edition of Circadian Physiology delves into the mechanisms surrounding how these rhythms work, the physiology and biology behind them, and the latest research on this cutting-edge field. The book also discusses a wide variety of practical topics including the prevention of jet lag, management of shift work,sleep disorders, depression, and the optimal times for physical and intellectual activities.

To facilitate its use as a textbook, the book contains summaries, suggestions for further reading, links to pertinent websites, and exercises at the end of each chapter. It also includes software for data analysis, tutorials, and simulation programs discussed throughout the text. In addition, more than a thousand references have been added, resulting in a total of more than 6000 references.

The text has been thoroughly updated as a result of major advances in recent years. This edition adds discussion on the anatomical and physiological characterization of photoresponsive ganglionic cells in the mammalian retina, molecular circadian clocks in cells of multiple organs other than the hypothalamus and the pineal gland, and advances in the understanding of post-translational mechanisms in the operation of the molecular clock.

Reviews

Praise for the Previous Edition:

"… the text remains one of the few comprehensive and scientific introductions to circadian physiology …"

—Roy Shephard, MD, PhD,Applied Physiology, University of Toronto, Canada

Table of Contents

HISTORY AND METHODS

Early Research on Circadian Rhythms

Remote Past

Twentieth Century

Current Trends

Ethics of Animal Research

Summary

Exercises

Suggestions for Further Reading

Websites to Explore

References

Research Methods in Circadian Physiology

Scientific Method

Research on Populations and Organisms

Research on Organs, Cells, and Molecules

Research on the Environment

Summary

Exercises

Suggestions for Further Reading

Websites to Explore

References

Analysis of Circadian Rhythmicity

Data Analysis

Parameters of Circadian Rhythms

Statistical Significance

Summary

Exercises

Suggestions for Further Reading

Websites to Explore

References

PHENOMENOLOGY

Ultradian and Infradian Rhythms

Environmental Rhythms

Ultradian Rhythms

Infradian Rhythms

Annual Rhythms

Summary

Exercises

Suggestions for Further Reading

Websites to Explore

References

Daily and Circadian Rhythms

Environmental and Populational Rhythms

Behavioral Rhythms

Autonomic Rhythms

Summary

Exercises

Suggestions for Further Reading

Websites to Explore

References

MECHANISMS

Endogenous Mechanisms

Endogenous Rhythmicity

Inheritance Mechanisms

Single or Multiple Oscillators

Summary

Exercises

Suggestions for Further Reading

Websites to Explore

References

Photic Environmental Mechanisms

Nonparametric Theory of Entrainment

Photic Parameters

Synthesis and Models

Summary

Exercises

Suggestions for Further Reading

Websites to Explore

References

Nonphotic Environmental Mechanisms

Nonphotic Entrainment

Searching for a Common Mechanism

Separate Food-Entrainable Pacemaker

Summary

Exercises

Suggestions for Further Reading

Websites to Explore

References

Integration of Mechanisms

Internal Temporal Order

Ecology and Evolution

Lifetime Changes

Summary

Exercises

Suggestions for Further Reading

Websites to Explore

References

Homeostasis and Circadian Rhythmicity

Temperature Regulation

Sleep, Feeding, and Energy Expenditure

Summary

Exercises

Suggestions for Further Reading

Websites to Explore

References

PHYSICAL SUBSTRATES

Receptors

Sensory Input

Photic Receptors

Nonphotic Receptors

Summary

Exercises

Suggestions for Further Reading

Websites to Explore

References

Pacemakers

Suprachiasmatic Nucleus

Cellular Processes

Molecular Processes

Other Pacemakers

Summary

Exercises

Suggestions for Further Reading

References

Afference and Efference

Afferent Pathways

Efferent Pathways

Summary

Exercises

Suggestions for Further Reading

Websites to Explore

References

APPLICATIONS

Optimal Timing on Earth and in Space

Patterns of Human Mobility

Best Time for Sports and Intellectual Activities

Space Exploration

Summary

Exercises

Suggestions for Further Reading

Websites to Explore

References

Jet-Lag and Shift Work

Jet-Lag Syndrome

Shift-Work Malaise

Daylight-Saving Time

Summary

Exercises

Suggestions for Further Reading

Websites to Explore

References

Human Medicine

Chronotherapeutics

Sleep Disorders

Depression

Summary

Exercises

Suggestions for Further Reading

Websites to Explore

References

Pet Selection and Veterinary Medicine

Pet Selection

Veterinary Medicine

Summary

Exercises

Suggestions for Further Reading

Websites to Explore

References

Appendix A: Assessment of Learning

Appendix B: Dictionary of Circadian Physiology

Appendix C: Organisms Used

About the Author

Roberto Refinetti, PhD, is a physiological psychology professor, circadian physiology researcher, and chair of the department of psychology at Boise State University in Idaho, USA. He is also a member of the graduate faculty of the University of Messina (Italy) and was formerly associated with the University of South Carolina, the University of Virginia, the University of Illinois, the University of São Paulo (Brazil), and the University of California at Santa Barbara, where he earned his doctorate. His research program in circadian physiology, which concentrates on the integration of circadian and homeostatic mechanisms, has been funded by the U.S. National Science Foundation and the National Institutes of Health. Professor Refinetti is editor-in-chief of the Journal of Circadian Rhythms and of the interdisciplinary journal Sexuality & Culture.

Subject Categories

BISAC Subject Codes/Headings:
MED005000
MEDICAL / Anatomy
MED045000
MEDICAL / Internal Medicine
PSY000000
PSYCHOLOGY / General
SCI086000
SCIENCE / Life Sciences / General
SCI089000
SCIENCE / Life Sciences / Neuroscience