3rd Edition

Handbook of Capillary and Microchip Electrophoresis and Associated Microtechniques

Edited By James P. Landers Copyright 2007
    1596 Pages 739 B/W Illustrations
    by CRC Press

    Although capillary electrophoresis (CE) technology has evolved quickly from the research laboratory into practical application in numerous fields, many scientists still debate its merits. While the body of international CE literature continues to expand dramatically, experts still question whether it has provided the speed, resolving power, peak capacity, sensitivity, robustness, and cost-reduction promised by its pioneers. Responding to these criticisms, this third edition brings together cutting-edge researchers to demonstrate the utility of CE across a broad spectrum of disciplines including—

  • Forensic science
  • Medical diagnostics
  • Pharmaceutical science
  • Genetic analysis
  • Biotechnology
  • Fluid mechanics
  • Environmental science
  • Biomedical research
  • Nanotechnology
  • Proteomics
  • Detailed Analysis of New Methodologies and Applications

    Eagerly awaited by researchers and technicians who transformed the first two editions into bestsellers, this latest volume once again delivers. Emphasizing microseparations and microfluidics, the Handbook of Capillary and Microchip Electrophoresis, Third Edition features new chapters describing the use of microchip electrophoresis and associated microtechniques, with a focus on the extraordinary breadth of work undertaken to expand CE methodologies in recent years. Aided by contributions from leading international experts, this text remains a seminal reference for numerous chemistry, biology, and engineering fields.

    Part I Fundamentals and Methodologies
    Introduction to Capillary Electrophoresis, J.P. Landers
    Protein Analysis by Capillary Electrophoresis, J.M. Hempe
    Micellar Electrokinetic Chromatography, S. Terabe
    Capillary Electrophoresis for Pharmaceutical Analysis, E. McEvoy, A. Marsh, K. Altria, S. Donegan, and Joe Power
    Principles and Practice of Capillary Electrochromatography, M.T. Koesdjojo, C.F. Gonzalez, and V.T. Remcho
    Capillary Electrophoresis of Nucleic Acids, E. Szántai and A. Guttman
    Analysis of Carbohydrates by Capillary Electrophoresis, J. Khandurina
    The Coupling of Capillary Electrophoresis and Mass Spectrometry in
    Proteomics, H.J. Issaq and T.D. Veenstra
    Light-Based Detection Methods for Capillary Electrophoresis, C. Scanlan, T. Lapainis, and J.V. Sweedler
    Microfluidic Devices for Electrophoretic Separations: Fabrication and Use, L. A. Legendre, J. P. Ferrance, and J.P. Landers
    Part IIA Capillary-Based Systems: Core Methods and Technologies
    Kinetic Capillary Electrophoresis, M.V. Berezovski and S.N. Krylov
    DNA Sequencing and Genotyping by Free-Solution Conjugate Electrophoresis, J.A. Coyne, J.S. Lin, and A. E. Barron
    Online Sample Preconcentration for Capillary Electrophoresis, D.S. Burgi and B.C. Giordano
    Capillary Electrophoresis for the Analysis of Single Cells: Sampling,
    Detection, and Applications, I. G. Arcibal, M.F. Santillo, and A.G. Ewing
    Ultrafast Electrophoretic Separations, M.G. Roper, C. Guillo, and B. J. Venton
    DNA Sequencing by Capillary Electrophoresis, D.L. Yang, R. Sauvageot, and S.L. Pentoney, Jr.
    Dynamic Computer Simulation Software for Capillary Electrophoresis, M.C. Breadmore and W. Thormann
    Heat Production and Dissipation in Capillary Electrophoresis, C.J. Evenhuis, R.M. Guijt, M. Macka, P.J. Marriott, and P.R. Haddad
    Isoelectric Focusing in Capillary Systems, J.W. T. Huang, and J. Pawliszyn
    Part IIB Capillary-Based Systems: Specialized Methods and Technologies
    Subcellular Analysis by Capillary Electrophoresis, B.G. Poe and E.A. Arriaga
    Chemical Cytometry: Capillary Electrophoresis Analysis at the Level of the
    Single Cell, C.Whitmore, K. Sobhani, R. Bonn, D. Mao, E. Turner, J. Kraly, D. Michels, M. Palcic, O. Hindsgaul, and N.J. Dovichi
    Glycoprotein Analysis by Capillary Electrophoresis, M. Girard, I. Lacunza, J.C. Diez-Masa, and M. de Frutos
    Capillary Electrophoresis of Post-Translationally Modified Proteins and Peptides, B. Sarg and H.H. Lindner
    Extreme Resolution in Capillary Electrophoresis: UHVCE, FCCE, and SCCE, W. H. Henley and J.W. Jorgenson
    Separation of DNA for Forensic Applications Using Capillary Electrophoresis, L.I. Moreno and B. McCord
    Clinical Application of CE, Z.K. Shihabi
    Solid-Phase Microextraction and Solid-Phase Extraction with Capillary Electrophoresis and Related Techniques, S. G. Weber
    CE-SELEX: Isolating Aptamers Using Capillary Electrophoresis, R.K. Mosing and M.T. Bowser
    Microfluidic Technology as a Platform to Investigate the Microcirculation, D.M. Spence
    Capillary Electrophoresis Applications for Food Analysis, B.Vallejo-Cordoba and M. G. Vargas Martínez
    Separation Strategies for Environmental Analysis, F. G. Tonin and M.F.M. Tavares
    Part IIIA Microchip-Based: Core Methods and Technologies
    Cell Manipulation at the Micron Scale, T. M. Keenan and D. J. Beebe
    Multidimensional Microfluidic Systems for Protein and Peptide Separations, D.L. DeVoe and C.S. Lee
    Microchip Immunoassays, K. Sato and T. Kitamori
    Solvent Extraction on Chips, M. Tokeshi and T. Kitamori
    Electrophoretic Microdevices for Clinical Diagnostics, J.P. Ferrance
    Advances in Microfluidics: Development of a Forensic Integrated DNA Microchip (IDChip), K.M. Horsman and J.P. Landers
    Taylor Dispersion in Sample Preconcentration Methods, R. Bharadwaj, D.E. Huber, T. Khurana, and J.G. Santiago
    The Mechanical Behavior of Films and Interfaces in Microfluidic Devices: Implications for Performance and Reliability, M.R. Begley and J. Monahan
    Practical Fluid Control Strategies for Microfluidic Devices, C.J. Easley and J.P. Landers
    Low-Cost Technologies for Microfluidic Applications, W.K. Tomazelli Coltro and E. Carrilho
    Microfluidic Reactors for Small Molecule and Nanomaterial Synthesis, A.J. deMello, C.J. Cullen, R. Fortt, and R.C.R. Wootton
    Part IIIB Microchip-Based: Specialized Methods and Technologies
    Sample Processing with Integrated Microfluidic Systems, J.M. Bienvenue and J.P. Landers
    Cell and Particle Separation and Manipulation Using Acoustic Standing Waves in Microfluidic Systems, T. Laurell and J.Nilsson
    Optical Detection Systems for Microchips, J.M. Karlinsey and J.P. Landers
    Microfabricated Electrophoresis Devices for High-Throughput Genetic Analysis: Milestones and Challenges, C.A. Emrich and R.A. Mathies
    Macroporous Monoliths for Chromatographic Separations in Microchannels, F. Svec and T.B. Stachowiak
    Microdialysis and Microchip Systems, B.A. Fogarty, P. Nandi, and S.M. Lunte
    Microfluidic Sample Preparation for Proteomics Analysis Using MALDI-MS, S. Ekström, J. Nilsson, G. Marko-Varga, and T. Laurell
    Implementing Sample Preconcentration in Microfluidic Devices, P. M. van Midwoud and E. Verpoorte
    Using Phase-Changing Sacrificial Materials to Fabricate Microdevices for Chemical Analysis, H V. Fuentes and A.T. Woolley
    Materials and Modification Strategies for Electrophoresis Microchips, C. S. Henry and B.M. Dressen
    Microfluidic Devices with Mass Spectrometry Detection, I. M. Lazar
    Nanoscale Self-Assembly of Stationary Phases for Capillary Electrophoresis of DNA, K.D. Dorfman and J.L. Viovy
    Nanoscale DNA Analysis, L. Mahmoudian, M.R. Mohamadi, N. Kaji, M. Tokeshi, and Y. Baba


    James P. Landers

    "This book is quite valuable theoretically and methodologically for specialists of various field of analytical chemistry and biochemistry, molecular biology, biotechnology, and medicine and also for teachers and students of colleges and universities specialized in Bioanalysis."

    Biochemistry (Moscow)