Handbook of Capillary and Microchip Electrophoresis and Associated Microtechniques: 3rd Edition (Hardback) book cover

Handbook of Capillary and Microchip Electrophoresis and Associated Microtechniques

3rd Edition

Edited by James P. Landers

CRC Press

1,592 pages | 739 B/W Illus.

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Although capillary electrophoresis (CE) technology has evolved quickly from the research laboratory into practical application in numerous fields, many scientists still debate its merits. While the body of international CE literature continues to expand dramatically, experts still question whether it has provided the speed, resolving power, peak capacity, sensitivity, robustness, and cost-reduction promised by its pioneers. Responding to these criticisms, this third edition brings together cutting-edge researchers to demonstrate the utility of CE across a broad spectrum of disciplines including—

  • Forensic science
  • Medical diagnostics
  • Pharmaceutical science
  • Genetic analysis
  • Biotechnology
  • Fluid mechanics
  • Environmental science
  • Biomedical research
  • Nanotechnology
  • Proteomics
  • Detailed Analysis of New Methodologies and Applications

    Eagerly awaited by researchers and technicians who transformed the first two editions into bestsellers, this latest volume once again delivers. Emphasizing microseparations and microfluidics, the Handbook of Capillary and Microchip Electrophoresis, Third Edition features new chapters describing the use of microchip electrophoresis and associated microtechniques, with a focus on the extraordinary breadth of work undertaken to expand CE methodologies in recent years. Aided by contributions from leading international experts, this text remains a seminal reference for numerous chemistry, biology, and engineering fields.


    "This book is quite valuable theoretically and methodologically for specialists of various field of analytical chemistry and biochemistry, molecular biology, biotechnology, and medicine and also for teachers and students of colleges and universities specialized in Bioanalysis."

    Biochemistry (Moscow)

    Table of Contents

    Part I Fundamentals and Methodologies

    Introduction to Capillary Electrophoresis, J.P. Landers

    Protein Analysis by Capillary Electrophoresis, J.M. Hempe

    Micellar Electrokinetic Chromatography, S. Terabe

    Capillary Electrophoresis for Pharmaceutical Analysis, E. McEvoy, A. Marsh, K. Altria, S. Donegan, and Joe Power

    Principles and Practice of Capillary Electrochromatography, M.T. Koesdjojo, C.F. Gonzalez, and V.T. Remcho

    Capillary Electrophoresis of Nucleic Acids, E. Szántai and A. Guttman

    Analysis of Carbohydrates by Capillary Electrophoresis, J. Khandurina

    The Coupling of Capillary Electrophoresis and Mass Spectrometry in

    Proteomics, H.J. Issaq and T.D. Veenstra

    Light-Based Detection Methods for Capillary Electrophoresis, C. Scanlan, T. Lapainis, and J.V. Sweedler

    Microfluidic Devices for Electrophoretic Separations: Fabrication and Use, L. A. Legendre, J. P. Ferrance, and J.P. Landers

    Part IIA Capillary-Based Systems: Core Methods and Technologies

    Kinetic Capillary Electrophoresis, M.V. Berezovski and S.N. Krylov

    DNA Sequencing and Genotyping by Free-Solution Conjugate Electrophoresis, J.A. Coyne, J.S. Lin, and A. E. Barron

    Online Sample Preconcentration for Capillary Electrophoresis, D.S. Burgi and B.C. Giordano

    Capillary Electrophoresis for the Analysis of Single Cells: Sampling,

    Detection, and Applications, I. G. Arcibal, M.F. Santillo, and A.G. Ewing

    Ultrafast Electrophoretic Separations, M.G. Roper, C. Guillo, and B. J. Venton

    DNA Sequencing by Capillary Electrophoresis, D.L. Yang, R. Sauvageot, and S.L. Pentoney, Jr.

    Dynamic Computer Simulation Software for Capillary Electrophoresis, M.C. Breadmore and W. Thormann

    Heat Production and Dissipation in Capillary Electrophoresis, C.J. Evenhuis, R.M. Guijt, M. Macka, P.J. Marriott, and P.R. Haddad

    Isoelectric Focusing in Capillary Systems, J.W. T. Huang, and J. Pawliszyn

    Part IIB Capillary-Based Systems: Specialized Methods and Technologies

    Subcellular Analysis by Capillary Electrophoresis, B.G. Poe and E.A. Arriaga

    Chemical Cytometry: Capillary Electrophoresis Analysis at the Level of the

    Single Cell, C.Whitmore, K. Sobhani, R. Bonn, D. Mao, E. Turner, J. Kraly, D. Michels, M. Palcic, O. Hindsgaul, and N.J. Dovichi

    Glycoprotein Analysis by Capillary Electrophoresis, M. Girard, I. Lacunza, J.C. Diez-Masa, and M. de Frutos

    Capillary Electrophoresis of Post-Translationally Modified Proteins and Peptides, B. Sarg and H.H. Lindner

    Extreme Resolution in Capillary Electrophoresis: UHVCE, FCCE, and SCCE, W. H. Henley and J.W. Jorgenson

    Separation of DNA for Forensic Applications Using Capillary Electrophoresis, L.I. Moreno and B. McCord

    Clinical Application of CE, Z.K. Shihabi

    Solid-Phase Microextraction and Solid-Phase Extraction with Capillary Electrophoresis and Related Techniques, S. G. Weber

    CE-SELEX: Isolating Aptamers Using Capillary Electrophoresis, R.K. Mosing and M.T. Bowser

    Microfluidic Technology as a Platform to Investigate the Microcirculation, D.M. Spence

    Capillary Electrophoresis Applications for Food Analysis, B.Vallejo-Cordoba and M. G. Vargas Martínez

    Separation Strategies for Environmental Analysis, F. G. Tonin and M.F.M. Tavares

    Part IIIA Microchip-Based: Core Methods and Technologies

    Cell Manipulation at the Micron Scale, T. M. Keenan and D. J. Beebe

    Multidimensional Microfluidic Systems for Protein and Peptide Separations, D.L. DeVoe and C.S. Lee

    Microchip Immunoassays, K. Sato and T. Kitamori

    Solvent Extraction on Chips, M. Tokeshi and T. Kitamori

    Electrophoretic Microdevices for Clinical Diagnostics, J.P. Ferrance

    Advances in Microfluidics: Development of a Forensic Integrated DNA Microchip (IDChip), K.M. Horsman and J.P. Landers

    Taylor Dispersion in Sample Preconcentration Methods, R. Bharadwaj, D.E. Huber, T. Khurana, and J.G. Santiago

    The Mechanical Behavior of Films and Interfaces in Microfluidic Devices: Implications for Performance and Reliability, M.R. Begley and J. Monahan

    Practical Fluid Control Strategies for Microfluidic Devices, C.J. Easley and J.P. Landers

    Low-Cost Technologies for Microfluidic Applications, W.K. Tomazelli Coltro and E. Carrilho

    Microfluidic Reactors for Small Molecule and Nanomaterial Synthesis, A.J. deMello, C.J. Cullen, R. Fortt, and R.C.R. Wootton

    Part IIIB Microchip-Based: Specialized Methods and Technologies

    Sample Processing with Integrated Microfluidic Systems, J.M. Bienvenue and J.P. Landers

    Cell and Particle Separation and Manipulation Using Acoustic Standing Waves in Microfluidic Systems, T. Laurell and J.Nilsson

    Optical Detection Systems for Microchips, J.M. Karlinsey and J.P. Landers

    Microfabricated Electrophoresis Devices for High-Throughput Genetic Analysis: Milestones and Challenges, C.A. Emrich and R.A. Mathies

    Macroporous Monoliths for Chromatographic Separations in Microchannels, F. Svec and T.B. Stachowiak

    Microdialysis and Microchip Systems, B.A. Fogarty, P. Nandi, and S.M. Lunte

    Microfluidic Sample Preparation for Proteomics Analysis Using MALDI-MS, S. Ekström, J. Nilsson, G. Marko-Varga, and T. Laurell

    Implementing Sample Preconcentration in Microfluidic Devices, P. M. van Midwoud and E. Verpoorte

    Using Phase-Changing Sacrificial Materials to Fabricate Microdevices for Chemical Analysis, H V. Fuentes and A.T. Woolley

    Materials and Modification Strategies for Electrophoresis Microchips, C. S. Henry and B.M. Dressen

    Microfluidic Devices with Mass Spectrometry Detection, I. M. Lazar

    Nanoscale Self-Assembly of Stationary Phases for Capillary Electrophoresis of DNA, K.D. Dorfman and J.L. Viovy

    Nanoscale DNA Analysis, L. Mahmoudian, M.R. Mohamadi, N. Kaji, M. Tokeshi, and Y. Baba


    Subject Categories

    BISAC Subject Codes/Headings:
    MEDICAL / Biochemistry
    SCIENCE / Chemistry / Analytic
    SCIENCE / Research & Methodology