738 pages | 14 Color Illus. | 125 B/W Illus.
In the quest for innovative drug delivery systems attempting to meet the unmet needs in pharmaceutical space, research has taken a much more complicated path that poses a significant challenge for translation. Despite the progress made with novel materials, polyesters still remain at the helm of drug delivery technologies. This book provides a single source of reference of polyester drug delivery systems that covers a broad spectrum of materials design, manufacturing techniques, and applications.
Overview of Synthesis of Functional Polyesters. Biodegradable Fatty Acid Polyesters. Enzymatically Synthesized Polyesters for Drug Delivery. Overview of Methods of Making Polyester Nano- and Microparticulate Systems for Drug Delivery. Electrospun Biodegradable Polyester Micro-/Nanofibers for Drug Delivery and Their Clinical Applications. Overview of Polylactide-co-Glycolide Drug Delivery Systems. Overview of Polycaprolactone-Based Drug Delivery Systems. Engineered PLGA Nanosystems for Enhanced Blood Compatibility. Peroral Polyester Drug Delivery Systems. Overview of Polyester Nanosystems for Nasal Administration. Polyester Particles for Drug Delivery to the Skin: Local and Systemic Applications. Aliphatic Polyester–Protein Delivery Systems. Biodegradable Polyester-Based Multicompartmental Delivery Systems for Oral Nucleic Acid Therapy. PLGA Nano- and Microparticles for VEGF Delivery. Polyester Nano- and Microsystems for Vaccine Delivery. Mucosal Immunization Using Polyester-Based Particulate Systems. Aliphatic Polyester Micro- and Nanosystems for Treating HIV, Tuberculosis, and Malaria. Polyester Nano- and Microtechnologies for Tissue Engineering. Polyester Particles for Curcumin Delivery. Polyester Carriers for Enzyme Delivery.