1st Edition
Medical Biotechnology, Biopharmaceutics, Forensic Science and Bioinformatics
This book covers a range of topics on exploiting Nigeria’s mega biodiversity for food security and health; DNA forensic science and its applications; medical biotechnology and biopharmaceutics; medicinal and underutilized plants; impact and mitigation of antibiotic resistance; bioinformatics applications; medical insect biotechnology; etc. The book will be useful reference material for the scientists and researchers working in the fields of nutraceuticals, molecular diagnostics and DNA forensics, biopharmaceuticals and medical biotechnology, nanotechnology, antimicrobials from indigenous plant species, bioinformatics, etc.
- Emphasizes recent advances in biotechnologies that will help in tackling emerging global health challenges
- Provides detailed information on how to harness indigenous bioresources including microorganisms and plants for healthcare delivery
- Introduces new frontiers in the areas of molecular diagnostics and DNA forensic science and bioinformatics with case studies, recent advances in medical insect biotechnology and molecular genetics of pest use towards the exploitation of arthropod midgut components to develop interventions against infectious diseases
- Reviews bioactive molecules derived from commonly used and underutilized medicinal plants that could be used to develop novel drugs for improved healthcare delivery
- Discusses current approaches in medical and biopharmaceutical biotechnology, deployment of inexpensive genomics-based vector surveillance for effective disease outbreak prediction and control of mosquito-borne viruses
Hajiya Mairo Inuwa, Ph.D., is Professor in the Department of Biochemistry and Formerly Director, Centre for Biotechnology Research and Training (CBR&T), Ahmadu Bello University, Zaria, Nigeria.
Ifeoma Maureen Ezeonu, Ph.D., is Professor of Medical Microbiology and Molecular Genetics in the Department of Microbiology, University of Nigeria, Nsukka, Nigeria.
Charles Oluwaseun Adetunji, Ph.D., is Associate Professor of Microbiology and Biotechnology and Director of Intellectual Property and Technology Transfer, Edo State University, Uzairue, Nigeria.
Abubakar Gidado, Ph.D., is Professor of Biochemistry and Director of North-East Zonal Biotechnology Centre of Excellence at the University of Maiduguri.
Emmanuel Olufemi Ekundayo, Ph.D., is Associate Professor of Medical Microbiology and Microbial Genetics, Michael Okpara University of Agriculture, Umudike, Nigeria.
Abdulrazak B. Ibrahim, Ph.D., is a Capacity Development Expert at the Forum for Agricultural Research in Africa (FARA) and Associate Professor of Biochemistry, Ahmadu Bello University, Zaria, Nigeria.
Benjamin Ewa Ubi, Ph.D., is a Professor of Plant Breeding and Biotechnology and Director, Biotechnology Research and Development Centre, Ebonyi State University, Abakaliki, Nigeria.
PART 1 Working Group 04: Molecular Diagnostics and DNA Forensics
Handling Editor: Prof. Ifeoma M. Ezeonu
Chapter 1 Principles and Techniques for Deoxyribonucleic Acid (DNA) Manipulation
Nwadiuto Esiobu, Ifeoma Ezeonu, and Francisca Nwaokorie
Chapter 2 Forensic DNA Profiling and Molecular Identification of Infectious Pathogens: The Nigeria Experience
D. E. Agbonlahor, M. Y. Tatfeng, I. B. Enweani-Nwokelo,
Ifeoma Ezeonu, E. A. Brisibe, Francisca Nwaokorie,
Nwadiuto Esiobu, A. O. Eremwanarue, F. E. Oviasogie,
and B. E. Ubi
Chapter 3 DNA Markers in Forensic and Diagnostic Science
M. Y. Tatfeng, D. E. Agbonlahor, I. B. Enweani-Nwokelo,
Ifeoma Ezeonu, Francisca Nwaokorie, E. A. Brisibe, and
D. Esiobu
Chapter 4 Legal Standards Setting in the Use of Forensics/DNA Barcode: Evidence for Wildlife Crime Detection and Prosecution in Nigeria
Christie O. Onyia, Obianuju P. Ilo, and Scott E. Miller
PART 2 Working Group 07: Medical and Pharmaceutical Biotechnology
Handling Editor: Prof. Hajiya Mairo Inuwa
Chapter 5 Harnessing Indigenous Bioresources for Development of Diagnostics for Detection and Confirmation of Infectious Agents in Nigeria
E. O. Ekundayo, J. C. Igwe, and Ifeoma Ezeonu
Chapter 6 Antibiotic Resistance: Global Trends, Impact and Mitigation
Ifeoma M. Ezeonu, Ifeanyi R. Iroha, and Nwadiuto Esiobu
Chapter 7 Safeguarding Nigeria Territory from the Use of Antibiotic Resistant Microbes in Bioterrorism
J. C. Igwe, E. O. Ekundayo, Ifeoma M. Ezeonu, and S. K. Parom
Chapter 8 Deep Learning and Economic Prospects in Medical and Pharmaceutical Biotechnology
Charles Oluwaseun Adetunji, Kingsley Eghonghon Ukhurebor,
Olugbemi Tope Olaniyan, Adetunji Juliana Bunmi,
Gloria E. Okotie, and Julius Kola Oloke
Chapter 9 Health and Nutritional Benefits of Numerous Bioactive Components Derived from Fish and Fish Products
Juliana Bunmi Adetunji, Charles Oluwaseun Adetunji,
Michael Olugbenga Samuel, Genevieve Dable-Tupas, and
Chukwuebuka Egbuna
Chapter 10 Repositioning Antiviral Drugs as a Rapid and Cost-Effective Approach to Discover Treatment against SARS-CoV-2 Infection
Omotayo Opemipo Oyedara, Folasade Muibat Adeyemi,
Charles Oluwaseun Adetunji, and Temidayo Oluyomi Elufisan
Chapter 11 Corn Silk and Health Benefits
Charles Oluwaseun Adetunji, Michael Olugbenga Samuel,
Adetunji Juliana Bunmi, and Oluranti OlufemiIdowu
Chapter 12 Bioengineering of Pharmacologically Active Metabolites for Effective Drug Nano-Formulations from the Callus
and Metabolites of Medicinal Plants and Their Significant Application in Nanomedicine: Recent Advances
Charles Oluwaseun Adetunji, Denisa Ficai, Anton Ficai,
Michael Olugbenga Samuel, Wilson Nwankwo,
Muhammad Akram, Chukwuebuka Egbuna,
Oluwaseyi Paul Olaniyan, Rumaisa Ansari, Hameed Shah,
Tehreen Riaz, Ruth Ebunoluwa Bodunrinde, Rida Zainab,
Adetunji Juliana Bunmi, Jonathan C. Ifemeje,
Mohammad Ali Shariati, Michael Chinedu Olisah,
Akinola Samson Olayinka, Kingsley Eghonghon Ukhurebor,
Daniel Ingo Hefft, and Wadzani Dauda Palnam
PART 3 Omics and Bioinformatics
Handling Editor: Charles Oluwaseun Adetunji
Chapter 13 Bioinformatics: A Tool for Biotechnological Advancement
O. M. Oyawoye, H. A. Olorunsola, A. O. Oluduro,
O. O. Bamigboye, E. K. Oladipo, T. M. Olotu, I. J. Adeosun,
M. O. Kaka, and O. O. Obembe
Chapter 14 Roles of Nucleotide Sequence Analysis in Human Genetics and Genomics
S. S. D. Mohammed, I. Abraham, D. Enoma, and L. E. Okoror
Chapter 15 Application of Computational and Bioinformatics Techniques in Drug Repurposing for Effective Development of Potential Drug Candidate for the Management of COVID-19
Charles Oluwaseun Adetunji, Olaniyan Tope Olugbemi,
Muhammad Akram, Umme Laila, Michael Olugbenga Samuel,
Ayomide Michael Oshinjo, Adetunji Juliana Bunmi,
Gloria E. Okotie, Nwadiuto Esiobu, Omotayo Opemipo Oyedara,
and Folasade Muibat Adeyemi
Chapter 16 Computational Intelligence Techniques for Combating COVID-19
Charles Oluwasun Adetunji, Wilson Nwankwo,
Akinola Samson Olayinka, Olaniyan Tope Olugbemi,
Muhammad Akram, Umme Laila, Michael Olugbenga Samuel,
Ayomide Michael Oshinjo, Adetunji Juliana Bunmi,
Gloria E. Okotie, and Nwadiuto Esiobu
Chapter 17 Machine Learning and Behaviour Modification for COVID 19....... 271
Charles Oluwasun Adetunji, Wilson Nwankwo,
Akinola Samson Olayinka, Olaniyan Tope Olugbemi,
Muhammad Akram, Umme Laila, Michael Samuel Olugbenga,
Ayomide Michael Oshinjo, Adetunji Julianah Bunmi,
Gloria E. Okotie, and Nwadiuto Esiobu
PART 4 Working Group 12: Medicinal and Underutilized Plants
Handling Editor: Prof. Abubakar Gidado
Chapter 18 Underutilized Plant Species: A Huge Potential for Economic Development in Nigeria
Friday Nwalo Nweke, Godwill Azeh Engwa, and
Oluchi Cynthia Abiamere
Chapter 19 The Place of Neglected Legumes in Human Nutrition and Food Security
Beckley Ikhajiagbe, Geoffrey Obinna Anoliefo,
Doris I. Omoigui, Edokpolor Osazee Ohanmu,
Saheed Ibrahim Musa, and Zipporah Emilomo Omage
Chapter 20 Antiprotozoal Activity of Some Medicinal Plants against
Entamoeba histolytica, the Causative Agent of Amoebiasis............ 341
Charles Oluwaseun Adetunji and Oyetunde T. Oyeyemi
Chapter 21 Harnessing Benefits of Underexploited Plant Species for
Economic Growth in Nigeria............................................................ 359
Ifeoma B. Enweani-Nwokelo, Ugoy Sonia A. Ogbonna,
Grace I. Okwu, and Onyekachukwu O. Enweani
PART 5 Working Group 13: Medical Insect Biotechnology, Genomics and Molecular Genetics of Pests
Handling Editor: Dr. Abdulrazak Ibrahim
Chapter 22 Exploiting Arthropod Midgut Components for Development of Interventions against Infectious Diseases
Oluwafemi Abiodun Adepoju, Bashiru Ibrahim, and
Emmanuel Oluwadare Balogun
Chapter 23 Applications of Metagenomics in Vector Surveillance for Effective Prediction and Control of Mosquito-Borne Viral
Disease Outbreaks
Nwadiuto Esiobu, Bamidele Oderinde, Njidda Gadzama, and
Ihekerenma Okoli
Biography
Hajia Mairo Inuwa, Ph.D. is Professor in the Dept. of Biochemistry & Formerly Director, Centre for Biotechnology Research and Training (CBR&T), Ahmadu Bello University, Zaria, Nigeria.
Ifeoma Maureen Ezeonu, Ph.D. is a Professor of Medical Microbiology and Molecular Genetics in the Department of Microbiology, University of Nigeria, Nsukka.
Charles Oluwaseun Adetunji, Ph.D. is Associate Professor of Microbiology and Biotechnology, & Director of intellectual Property and Technology Transfer, Edo State University Uzairue, Nigeria
Abubakar Gidado, Ph.D. is a Professor of Biochemistry and Director North-East Zonal Biotechnology Centre of Excellence at University of Maiduguri.
Emmanuel Olufemi Ekundayo, Ph.D. is an Associate Professor of Medical Microbiology and Microbial Genetics, Michael Okpara University of Agriculture, Umudike, Nigeria.
Abdulrazak Ibrahim, Ph.D. is a Capacity Development Expert at the Forum for Agricultural Research in Africa (FARA), and Associate Professor of Biochemistry, Ahmadu Bello University, Zaria, Nigeria.
Benjamin Ewa Ubi, Ph.D. is Professor of Plant Breeding and Biotechnology & Director, Biotechnology Research and Development Centre, Ebonyi State University Abakaliki, Nigeria.
