Micronutrients and HIV Infection: 1st Edition (Hardback) book cover

Micronutrients and HIV Infection

1st Edition

Edited by Henrik Friis

CRC Press

272 pages | 36 B/W Illus.

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Hardback: 9780849300851
pub: 2001-09-14
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Description

Analogous to other infections, evidence suggests that improved micronutrient intake may reduce HIV transmission and progression, as well as morbidity from common and opportunistic infections. This is important information, considering many in the world's HIV-infected population do not yet have access to anti-retroviral drugs. Micronutrients and HIV Infection presents current knowledge on the role of micronutrients in HIV and other infections - knowledge that can be used to improve case management and public health interventions.

The book provides a comprehensive overview of micronutrients and HIV infection through a review of recently published human studies and intervention trials and other important epidemiology based literature. It begins by introducing the malnutrition-infection complex, Nutritionally Acquired Immune Deficiency Syndrome, and the role of oxidative stress in infection. Then the book covers the history, biochemistry, biological functions, and food sources of individual micronutrients, and reviews their roles in host defense and resistance to infections in general, and HIV in particular. Finally, the book discusses how this information can be applied for the benefit of individuals with HIV and countries where HIV is widespread and treatment unavailable.

Most of the world's 35 million people living with HIV are micronutrient deficient and have little access to HIV testing, counseling, and care. In addition to covering specific micronutrients, Micronutrients and HIV Infection presents a critical review of how existing micronutrient interventions can be promoted, expanded, and modified to reduce the magnitude and impact of the HIV pandemic.

Reviews

"Nineteen authors from 6 countries, 11 of them with medical degrees, contributed the 11 chapters (citing 1009 references) of this very readable and well-edited book. …For a multi-authored volume, Micronutrients and HIV Infection has remarkably and refreshingly little redundancy. Moreover, some authors discuss the adverse consequences of excessive nutrient exposure on the course of HIV and opportunistic infections and the nutrient-nutrient interactions that can arise from nutrient interventions. The book also offers some priceless teaching illustrations."

- Noel W. Solomons and Monica Orozco in American Journal of Clinical Nutrition, Vol. 25

Table of Contents

MICRONUTRIENTS AND INFECTIONS: AN INTRODUCTION

Micronutrients and Infections

Micronutrient Requirements

Global Nutritional Situation

Micronutrients during the HIV Pandemic

NUTRITIONALLY ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Host Defensive Mechanisms Impaired by NAIDS

Varieties of NAIDS

Future Studies in Nutritional Immunology

OXIDATIVE STRESS AND INFECTIONS

Generation of ROS

Role of ROS

Damage from Excessive Production of ROS

Antioxination Defense System

Evidence of Oxidatives Stress during Viral Infections

VITAMIN A, CAROTENOIDS, AND HIV INFECTION

Historical Background

Epidemiology

Metabolism

Biological Functions of Vitamin A and Carotenoids

Pathophysiology of Vitamin A Deficiency

Assessment of Vitamin A and Carotenoid Status

Prevention of Vitamin A Deficiency

Conclusions

B VITAMINS AND HIV INFECTION

History, Biological Functions, Dietary Sources, and Dietary Requirements

Immune Function

HIV Infection

Conclusions

VITAMINS C AND E, AND HIV INFECTION

Vitamin C

Vitamin C and the Common Cold

Vitamin C Deficiency and HIV Infection

Vitamin E

Vitamin E Deficiency and HIV Infection

Conclusion

IRON AND HIV INFECTION

Historical Background

Iron Balance

Iron and HIV Infection

Iron and Opportunistic Infections

Perspectives and Conclusions

ZINC AND HIV INFECTION

Historical Background

Metabolism and Biological Functions

Assessment of Status

Dietary Requirements and Food Sources

Host Defense

Infection

HIV Infection

SELENIUM AND HIV INFECTION

Historical Background

Metabolism and Biological Functions

Assessment of Status

Dietary Requirements and Food Sources

Host Defense and Infections

HIV Infection

Perspectives and Conclusions

MICRONUTRIENTS IN THE CASE MANAGEMENT OF HIV INFECTION

Micronutrient Deficiencies in HIV Infection

Micronutrient Interventions

Case Management Strategies

Unresolved Issues

MICRONUTRIENT INTERVENTIONS AND THE HIV PANDEMIC

Micronutrients of Importance to HIV Infection

Multiple Micronutrient Deficiencies and Interactions

Determinants of Micronutrient Deficiencies

Micronutrient Interventions

Research Priorities

Conclusion

Note: Each Chapter includes an Introduction and References

About the Series

Modern Nutrition

Learn more…

Subject Categories

BISAC Subject Codes/Headings:
MED060000
MEDICAL / Nutrition