The Scope of Preclinical Drug Development: An Introduction and Framework; Mark C. Rogge
Lead Molecule Selection: Pharmaceutical Profiling and Toxicity Assessments; P. L. Bullock
Interspecies Differences in Physiology and Pharmacology: Extrapolating Preclinical
Data to Human Populations; M. N. Martinez
Pharmacokinetics/ADME of Small Molecules; A. D. Ajavon and David R. Taft
Pharmacokinetics/ADME of Large Molecules; R. Braeckman
Preclinical Pharmacokinetic–Pharmacodynamic Modeling and Simulation in Drug Development; P. L. Bonate and P. Vicini
Formulation and Production Strategies for Enhancing Bioavailability of Poorly Absorbed Drugs; A. B. Watts and R. O. Williams III
Transporters Involved in Drug Disposition, Toxicity, and Efficacy; C. Q. Xia and G. T. Miwa
Toxicity Evaluations, ICH Guidelines, and Current Practice; J. L. Larson
Application of Pathology in Safety Assessment; Robert A. Ettlin and David E. Prentice
Utilizing the Preclinical Database to Support Clinical Drug Development; H. Lee
Index
Biography
Mark Rogge, David R. Taft
'...an excellent book covering important aspects of preclinical drug development. All chapters are well-written...' - The British Toxicology Society Newsletter
