1st Edition

Herbal Bioactives and Food Fortification Extraction and Formulation

By D. Suresh Kumar Copyright 2016
    274 Pages 30 B/W Illustrations
    by CRC Press

    Recent major shifts in global health care management policy have been instrumental in renewing interest in herbal medicine. However, literature on the development of products from herbs is often scattered and narrow in scope. Herbal Bioactives and Food Fortification: Extraction and Formulation provides information on all aspects of the extraction of biological actives from plants and the development of dietary supplements and fortified food using herbal extracts.

    The book begins with a brief survey of the use of herbs in different civilizations and traces the evolution of herbal medicine, including the emergence of nutraceuticals from the discipline of ethnopharmacology and the Alma Ata Declaration of 1978. It moves on to describe various aspects of the extraction process, including selection of plant species, quality control of raw materials, the comminution of herbs, and the selection of solvents. It also describes the optimization of extraction in relation to response surface methodology before describing uses of herbal extracts in food supplements and fortified foods.

    With special attention paid to stability analysis and the masking of tastes, the book gives an overview of the formulation of various types of tablets, capsules, and syrups using herbal extracts. It also describes the benefits of foods fortified with herbal extracts such as soups, yogurt, sauces, mayonnaise, pickles, chutneys, jams, jellies, marmalades, cheese, margarine, sausages, bread, and biscuits, as well as some beverages.

    Herbal Bioactives and Food Fortification covers the fundamental steps in herbal extraction and processing in a single volume. It explains how to choose, optimize, analyze, and use extracts for fortification, making it an excellent source for nutraceutical researchers and practitioners in science and industry.

    Medical Herbalism through the Ages
    The "Iceman" Used Natural Laxatives
    Herbs in Different Civilizations
    Herbal Medicine in Medieval Europe
    Herbal Medicine in America
    Decline of Herbal Medicine
    Renewed Interest in Herbal Medicine
    Emergence of Nutraceuticals
    Nutraceuticals in Indian Medicine
    Proven Benefits of Nutraceuticals
    Outlook for the Future
    Concluding Remarks

    Bioactives from Plants
    Amazing Chemical Laboratories
    Biogenesis of Secondary Metabolites
    Functions of Secondary Metabolites
    Variation in Chemical Content of Herbs
    Good Cultivation Practices
    Modern Methods of Extraction of Bioactives
    Concluding Remarks

    Extraction of the Bioactives
    Selection of Plant Species
    Procuring Initial Samples of the Herb
    Procuring Larger Consignments of Herbs
    Quality Control of Raw Material
    Traceability of Herbs
    Cleaning of Herbs
    Comminution of Herbs
    Selection of Extraction Solvent
    Extraction of Herbs
    Pilot-Scale Extraction
    Enrichment of Extract
    Analysis of Extract
    Specification for the Extract
    Costing of the Extract
    Unit Recovery
    Stability Studies
    Toxicological Studies
    Material Safety Data Sheet (MSDS)
    Commercial Manufacture of the Extract
    Quality Assurance of Extracts
    Interaction with Marketing Team
    Concluding Remarks

    Supercritical Fluid Extraction of Bioactives
    Solubility of Compounds in Supercritical CO2
    The SCF Extraction Process
    Applications of SCF Technology
    Disadvantages of SCF Technology
    Concluding Remarks

    Formulation of Food Supplements
    Food Supplements
    Hygroscopicity of Extracts
    Removal of Interfering Substances
    Dosage Forms
    Concluding Remarks

    Food and Beverages Fortified with Phytonutrients
    Demonstration of Functional Effects
    Interesting Classes of Foods That Can Be Fortified
    Stability of Food
    Official Methods of Analysis
    Management of Product Quality
    Concluding Remarks


    D. Suresh Kumar earned his PhD from Banaras Hindu University, Varanasi, India, in 1977. In 1986, he joined the International Institute of Ayurveda, Coimbatore, as a research officer in the Department of Physiology. From 1986 to 2003, he conducted research on various aspects of Ayurveda. In collaboration with Dr. Y.S. Prabhakar, he proposed the first mathematical model for the ayurvedic concept of tridōṣa in the disease state. He also offered a novel definition for the ayurvedic class of medicine arka, based on his study of the Sanskrit text Arkaprakāśa. From 2003 to 2012 he was senior scientist in the Research and Development Centre of Sami Labs Ltd., Bangalore, where he worked on various aspects of product development and developed processes for the extraction of five nutraceuticals. He is currently the head of the research and development laboratory at the Ayurveda consortium, Confederation for Ayurveda Renaissance Keralam Ltd., Koratty, Kerala.