1st Edition

Handbook of Nutraceuticals Volume II Scale-Up, Processing and Automation

By Yashwant Vishnupant Pathak Copyright 2011
    596 Pages 131 B/W Illustrations
    by CRC Press

    594 Pages 131 B/W Illustrations
    by CRC Press

    Due in part to an absence of universally accepted standardization methods, nutraceuticals and functional foods face regulatory ignorance, marketing incompetence and ethical impunity. Even though many researchers believe that there is a connection between nutraceuticals and functional foods and reduced health care expenses as well as disease prevention, the credibility and quality control challenge remains. The industry needs more standardized testing, reliable reproducible clinical studies to prove the efficacies of products in vivo, and in-process controls to maintain universal product quality.

    The first volume of the Handbook of Nutraceuticals re-defined Nutraceuticals, covering the regulatory aspect as well as insisting on the cGMP’s and SOP’s for the nutraceutical manufacturing. This second volume focuses on the scale up, processing, and automation of nutraceutical production under cGMP production regulations. It covers:

    • Advancements in extraction methods
    • Unit operations involved in scaling up and processing
    • Rheological and flow properties of products as characterization parameters
    • Fortification and value enhancement using nanotechnology
    • Green concepts in food industry
    • Flavoring of nutraceuticals
    • Clinical batch nutraceutical manufacturing
    • New technologies to prevent counterfeiting
    • Automation in nutraceutical industry

    The nutraceutical market is at the crossroads. With a nearly $200 billion market for nutraceuticals and functional foods by end of 2013, and promising developments in product design and discovery, the industry must be ready for intense scrutiny. The standardization of testing, clinical studies, and adherence to rigorous industry and scientific methods is necessary for the advancement, acceptance, and development of high quality, effective nutraceuticals. With contributions from leading authorities, this book brings together hundreds of years of combined experience to provide guidance on how to increase the quality and credibility of nutraceutical products.

    Nutraceuticals: Advancing In a Right Direction,
    Uyen Lee and Yashwant Pathak
    Advances in Extraction of Plant Products in Nutraceutical Processing,
    Lijun Wang
    Liquid-Liquid Extraction and Adsorption Applied to the Processing of Nutraceuticals and Functional Foods,
    Antonio J. A. Meirelles, Eduardo A. C. Batista, Mariana C. Costa, and Marcelo Lanza

    Application of Enzyme Assisted Oil Extraction Technology in the Processing of Nutraceuticals and Functional Food,
    María Elvira Zúñiga, Carmen Soto, Jacqueline Concha, Eduardo Pérez

    Nutraceutical Processing Using Mixing Technology: Theory and Equipment,
    Sri Hyndhavi Ramadugu, Vijay Kumar Puli, and Yashwant Pathak
    Separation Technologies in Nutraceutical Processing,
    Vijay Kumar Puli, Sri Hyndhavi Ramadugu, and Yashwant Pathak
    Size Reduction Particle Size and Shape Characterization of Nutraceuticals,
    Sri Hyndhavi Ramadugu, Vijay Kumar Puli and Yashwant Pathak
    Application of spray drying technology for nutraceuticals and functional food products,
    Donald Chiou and Timothy A.G. Langrish
    Rheology of Complex Fluids Containing Nutraceuticals,
    Samiul Amin and Krassimir P. Velikov
    Scaling Up and Processing Nutraceutical Dispersions: Emulsions and Suspensions,
    Jayant Lokhande and Yashwant Pathak
    Validation of Nutraceutical Process Equipment,
    Don Rosendale
    Bio-processing of Marine Products for Nutraceuticals and Functional Food Products,
    Se-Kwon Kim, Isuru Wijesekara, and Dai-Hung Ngo
    The Packaging of Nutraceuticals Derived From Plants,
    Melvin A. Pascall
    Addressing Powder Flow and Segregation Concerns During Scale-Up of Nutraceutical Solid Formulations,
    Thomas Baxter, James Prescott, Roger Barnum, Jayant Khambekar
    Complying with FDA regulations for the manufacture and Quality control of Nutraceuticals: Do What You Say, Say What You Do,
    Mike Witt, Girish J. Kotwal and Yashwant V. Pathak
    Fortification and Value Enhancement of Food Products during Nutraceutical Processing using Microencapsulation and Nanotechnology,
    Xiaoqing Yang, Yuping Huang, and Qingrong Huang
    Apple Nutraceuticals and the Effects of Processing, and their Therapeutic Applications,
    John Eatough and Brian Lockwood
    Green Concepts in Food Industry,
    Anwesha Sarkar, Shantanu Das, Dilip Ghosh and Harjinder Singh
    Flavoring of Nutraceuticals,
    Aparna Keskar and William Igou Jr.
    Nutraceutical Clinical Batch Manufacturing,
    Weiyuan Chang
    New technologies protect nutraceuticals against counterfeiting,
    Roland Meylan
    Automated Manufacturing of Nutraceuticals,
    Naresh Rajanna


    Yashwant Pathak, PhD, Department of Pharmaceutical Sciences, Sullivan University College of Pharmacy, Louisville, Kentucky, USA